Gene Information gene info

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GENE：NIT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NIT1
FullNmae nitrilase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7828
EnsembleID ENSG00000158793
Uniprot Q86X76

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NIT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NIT1 GO:0005634,GO:0005737,GO:0005739,GO:0043605,GO:0110050

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 NIT1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MYC NIT1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 NIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NIT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000184017 NIT1 20065103 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000184017 NIT1 20065103 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CHCHD2 NIT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFB9 NIT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP5PO NIT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ZNRD2 NIT1 25348397 N/A physical interaction ComPPI
ZFYVE9 NIT1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PTS NIT1 25348397 N/A physical interaction ComPPI
NF2 NIT1 25348397 N/A physical interaction ComPPI
CD2AP NIT1 25348397 N/A physical interaction ComPPI
NIT1 XRCC6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NIT1 CUX1 25348397 N/A physical interaction ComPPI
NIT1 ADI1 25348397 N/A physical interaction ComPPI
NIT1 CAPN1 25348397 N/A physical interaction ComPPI
NIT1 GLRX 25348397 N/A physical interaction ComPPI
NIT1 NEDD8 25348397 N/A physical interaction ComPPI
NIT1 NDUFA11 24234451 24344204 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NIT1 C1QBP 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NIT1 IDE 25348397 N/A physical interaction ComPPI
NIT1 TOP3A 25348397 N/A physical interaction ComPPI
NIT1 BCKDK 25348397 N/A physical interaction ComPPI
NIT1 SIRT3 25348397 N/A physical interaction ComPPI
NIT1 TAZ 25348397 N/A physical interaction ComPPI
NIT1 BCAT2 25348397 N/A physical interaction ComPPI
NIT1 PDPR 25348397 N/A physical interaction ComPPI
NIT1 TUBA4A 25348397 N/A physical interaction ComPPI
NIT1 CLPX 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NIT1 TRIM25 25348397 N/A physical interaction ComPPI
NIT1 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 SLC16A1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 ATP5F1C 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 GFM1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 UQCRC2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 SHMT2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 ATP5PB 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 STOML2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 ATP5ME 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 ATP5PD 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFV3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 IMMT 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 GLRX5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFV2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 MRPL13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 TSFM 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 ACAD9 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 UQCRFS1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 UQCRB 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFC2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFAF1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 HTRA2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB11 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA12 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFV1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB10 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 COX6C 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS6 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA10 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA6 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS5 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFA9 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS8 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFS3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFB7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 ECI2 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 UQCR10 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NIPSNAP1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 MRPL16 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 SCO1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 NDUFAB1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NIT1 CYC1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
POLDIP2 NIT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECH1 NIT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NIPSNAP3A NIT1 25348397 N/A physical interaction ComPPI

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