GENE:SHQ1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SHQ1 |
| FullNmae | SHQ1, H/ACA ribonucleoprotein assembly factor |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25543 |
| EnsembleID | ENSG00000144736 |
| Uniprot | Q6PI26 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SHQ1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SHQ1 | GO:0000493,GO:0005515,GO:0005654,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0022618,GO:0043065,GO:0051082,GO:1904874,GO:2000233 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SHQ1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | SHQ1 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | SHQ1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | SHQ1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP63 | SHQ1 | 17521434 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SHQ1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| IGF1R | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | SHQ1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GMCL1 | SHQ1 | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RUVBL1 | SHQ1 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | SHQ1 | 25348397 | N/A | physical interaction | ComPPI |
| EXOSC4 | SHQ1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GAR1 | SHQ1 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | SHQ1 | 25348397 | N/A | physical interaction | ComPPI |
| RUVBL2 | SHQ1 | 25348397 | N/A | physical interaction | ComPPI |
| DGCR8 | SHQ1 | 25348397 | N/A | physical interaction | ComPPI |
| DKC1 | SHQ1 | 22085966 25348397 26186194 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| GMCL2 | SHQ1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| WDR48 | SHQ1 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SHQ1 | NAF1 | 12228251 21931644 24234451 25348397 26496610 27898060 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct,OmniPath |
| SHQ1 | GPR156 | 25348397 | N/A | physical interaction | ComPPI |
| SHQ1 | KNOP1 | 25348397 | N/A | physical interaction | ComPPI |
| SHQ1 | ZNHIT2 | 25348397 | N/A | physical interaction | ComPPI |
| SHQ1 | NOP10 | 22117216 27898060 | N/A | N/A | OmniPath |
