Gene Information gene info

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GENE：TIAM2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TIAM2
FullNmae TIAM Rac1 associated GEF 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11806
EnsembleID ENSG00000146426
Uniprot Q8IVF5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TIAM2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TIAM2 GO:0005085,GO:0005096,GO:0005829,GO:0007264,GO:0016020,GO:0030027,GO:0030175,GO:0030426,GO:0043204,GO:0045202,GO:0050772,GO:0051056,GO:0070062,GO:0090630

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 TIAM2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TIAM2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 TIAM2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TIAM2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TIAM2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TIAM2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TIAM2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TIAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000039E1E1 TIAM2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002FF522 TIAM2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005E6F45 TIAM2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TIAM2 PARD3 25361965 interaction type N/A PTMCode2
PARD3 TIAM2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TK1 TIAM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PKHD1 TIAM2 25348397 N/A in vitro,in vivo ComPPI
PARD3 TIAM2 14525934 15723051 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TNIK TIAM2 25348397 N/A physical interaction ComPPI
RNF2 TIAM2 25348397 N/A physical interaction ComPPI
SH3GL2 TIAM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H2AX TIAM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UFD1 TIAM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TIAM2 DISC1 25348397 N/A physical interaction ComPPI
TIAM2 DNM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TIAM2 ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TIAM2 PRKDC 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B4315 TIAM2 27087310 direct interaction,inhibition N/A NPInter

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