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GENE：YAF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol YAF2
FullNmae YY1 associated factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17363
EnsembleID ENSG00000015153
Uniprot Q8IY57

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
YAF2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
YAF2 GO:0003677,GO:0003712,GO:0003713,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006355,GO:0045892,GO:0045893,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
YAF2 hsa:10138 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 YAF2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 YAF2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 YAF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 YAF2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 YAF2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 YAF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004719AB YAF2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 YAF2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 YAF2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD231 YAF2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032BDF4 YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000FC8EB YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000096022 YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF YAF2 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
COL1A2 YAF2 25348397 N/A physical interaction ComPPI
PCBP1 YAF2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
E2F6 YAF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
SKP1 YAF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
GABPB1 YAF2 11953439 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
BMI1 YAF2 20601937 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
RING1 YAF2 21516116 24234451 25348397 25416956 27705803 association,physical association two hybrid,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RYBP YAF2 25348397 N/A physical interaction ComPPI
PCGF2 YAF2 20601937 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
CBX1 YAF2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
USP7 YAF2 25348397 N/A physical interaction ComPPI
UBB YAF2 25348397 N/A physical interaction ComPPI
MYC YAF2 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CSNK2A1 YAF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
CTR9 YAF2 25348397 N/A physical interaction ComPPI
ARF6 YAF2 25348397 N/A physical interaction ComPPI
CSNK2A2 YAF2 23455922 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
MDM2 YAF2 25348397 N/A physical interaction ComPPI
YY1 YAF2 14525934 24234451 25348397 9016636 physical association two hybrid,experimental interaction detection,physical interaction,imaging technique,in vitro,two hybrid ComPPI,HPRD,IntAct
HDAC2 YAF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
MXD1 YAF2 25348397 N/A physical interaction ComPPI
RNF2 YAF2 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,physical interaction,comigration in non denaturing gel electrophoresis,tandem affinity purification ComPPI,IntAct
TFDP1 YAF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
BCOR YAF2 24234451 25348397 26496610 27505670 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
CAND1 YAF2 25348397 N/A physical interaction ComPPI
YAF2 MYCN 11593398 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
YAF2 CBX3 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 ZFP42 25348397 N/A physical interaction ComPPI
YAF2 PCGF1 24234451 25348397 27505670 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 PCGF3 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 PCGF5 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 PCGF6 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 L3MBTL2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 MGA 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 BCORL1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 KDM2B 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 FBRS 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 XAGE1A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YAF2 SETBP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YAF2 AUTS2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 MYH13 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAF2 AGGF1 25348397 N/A physical interaction ComPPI
YAF2 MORC4 25348397 N/A physical interaction ComPPI
YAF2 ZNF622 25348397 N/A physical interaction ComPPI
YAF2 CHD8 25348397 N/A physical interaction ComPPI
YAF2 MLLT1 25348397 N/A physical interaction ComPPI
YAF2 FBXO7 25348397 N/A physical interaction ComPPI
YAF2 DCAF7 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 UBXN1 25348397 N/A physical interaction ComPPI
YAF2 ATF7IP 25348397 N/A physical interaction ComPPI
YAF2 PAF1 25348397 N/A physical interaction ComPPI
YAF2 FBRSL1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 UBE2S 25348397 N/A physical interaction ComPPI
YAF2 ARID4B 25348397 N/A physical interaction ComPPI
YAF2 COL1A1 25348397 N/A physical interaction ComPPI
YAF2 CSNK2B 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 DCAF6 25348397 N/A physical interaction ComPPI
YAF2 PDCD5 25348397 N/A physical interaction ComPPI
YAF2 MAX 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
YAF2 TRIM33 20603019 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
YAF2 ZNF689 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
WDR5 YAF2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM26 YAF2 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009C1B71 YAF2 27087310 direct interaction,inhibition N/A NPInter

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