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GENE：PLCD3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLCD3
FullNmae phospholipase C delta 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9061
EnsembleID ENSG00000161714
Uniprot Q8N3E9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLCD3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLCD3 GO:0001525,GO:0004435,GO:0005654,GO:0005737,GO:0005886,GO:0005886,GO:0016042,GO:0032154,GO:0035556,GO:0042127,GO:0046872,GO:0060716

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLCD3 hsa:113026 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
PLCD3 hsa:113026 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PLCD3 hsa:113026 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
PLCD3 hsa:113026 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)
PLCD3 hsa:113026 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
PLCD3 hsa:113026 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
PLCD3 hsa:113026 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 PLCD3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PLCD3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PLCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PLCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PLCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PLCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PLCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PLCD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PLCD3 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00003CF1AD PLCD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000008A99 PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C770D PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002152A8 PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000043C1C3 PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A760 PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003FBC84 PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122F23 PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006372A PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CC4BD PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 PLCD3 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SKIL PLCD3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CASQ2 PLCD3 25348397 N/A physical interaction ComPPI
UBE2A PLCD3 25348397 N/A physical interaction ComPPI
EAF1 PLCD3 25348397 N/A physical interaction ComPPI
EFNB3 PLCD3 25348397 N/A physical interaction ComPPI
ARIH1 PLCD3 25348397 N/A physical interaction ComPPI
SYNPO PLCD3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIP4K2A PLCD3 25348397 N/A physical interaction ComPPI
PLCD3 ARHGAP22 25348397 N/A physical interaction ComPPI

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