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GENE：CRTC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CRTC3
FullNmae CREB regulated transcription coactivator 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26148
EnsembleID ENSG00000140577
Uniprot Q6UUV7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CRTC3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CRTC3 GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0008140,GO:0016042,GO:0032793,GO:0042116,GO:0045944,GO:0050995,GO:0051289,GO:0071878,GO:0097009

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CRTC3 hsa:64784 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CRTC3 CREB1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR CRTC3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 CRTC3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CRTC3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CRTC3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 CRTC3 16980608 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CRTC3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 CRTC3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CRTC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002B7450 CRTC3 23313552 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS0000042E1F CRTC3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 CRTC3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001E96DA CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000019D79B CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000364FEF CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001799A3 CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000048F59D CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCDA3 CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 CRTC3 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 CRTC3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 CRTC3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 CRTC3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA CRTC3 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CRTC3 YWHAG 25361965 interaction type N/A PTMCode2
YWHAG CRTC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
YWHAG CRTC3 14525934 15324660 20936779 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo ComPPI,HPRD,IntAct
MCM2 CRTC3 25348397 N/A physical interaction ComPPI
EGLN3 CRTC3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
CBY1 CRTC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAPK8 CRTC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAB CRTC3 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA5 CRTC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LRP8 CRTC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EWSR1 CRTC3 25348397 N/A physical interaction ComPPI
XPO1 CRTC3 25348397 N/A physical interaction ComPPI
CLTC CRTC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 CRTC3 25348397 N/A physical interaction ComPPI
POLD1 CRTC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CENPJ CRTC3 24234451 25348397 26496610 26638075 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TRIM25 CRTC3 25348397 N/A physical interaction ComPPI
CGN CRTC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF13B CRTC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DCAF7 CRTC3 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
ZBTB21 CRTC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KCTD3 CRTC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SCYL1 CRTC3 25348397 N/A physical interaction ComPPI
KLHL12 CRTC3 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
CRTC3 NEDD1 25348397 N/A physical interaction ComPPI
CRTC3 MAGEA10 25348397 N/A physical interaction ComPPI
CRTC3 HCCS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRTC3 GTSE1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRTC3 PCDHB15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRTC3 CFAP97 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRTC3 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CRTC3 CA13 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRTC3 BCL3 17644518 27898060 stimulant N/A OmniPath
SIK1 CRTC3 16817901 27898060 inhibition N/A OmniPath

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