Gene Information gene info

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GENE：DTX3L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DTX3L
FullNmae deltex E3 ubiquitin ligase 3L
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30323
EnsembleID ENSG00000163840
Uniprot Q8TDB6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DTX3L immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DTX3L GO:0000077,GO:0002230,GO:0004842,GO:0004842,GO:0004857,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005765,GO:0005769,GO:0005829,GO:0005829,GO:0006302,GO:0006511,GO:0007219,GO:0008333,GO:0015031,GO:0019899,GO:0031901,GO:0032092,GO:0032991,GO:0035563,GO:0042393,GO:0042393,GO:0044389,GO:0045087,GO:0045893,GO:0046872,GO:0051444,GO:0051607,GO:0051865,GO:0070936,GO:0097677,GO:0140768,GO:0140852,GO:0140861,GO:1900182,GO:1902966,GO:2000646

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DTX3L hsa:151636 path:hsa04330 Notch signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 DTX3L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DTX3L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DTX3L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DTX3L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DTX3L 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D DTX3L 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00000AD002 DTX3L 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C4B1 DTX3L 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000007F792 DTX3L 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032835F DTX3L 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CC4BD DTX3L 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 DTX3L 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000482389 DTX3L 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 DTX3L 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC DTX3L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 DTX3L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 DTX3L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C DTX3L 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A DTX3L 23706177 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
UBE2I DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STAT1 DTX3L 25348397 N/A physical interaction ComPPI
UBE2D1 DTX3L 12670957 14525934 19549727 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
H2BC4 DTX3L 25348397 N/A physical interaction ComPPI
UBE2R2 DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E2 DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D4 DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
H4C1 DTX3L 25348397 N/A physical interaction ComPPI
RNF111 DTX3L 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D2 DTX3L 12670957 14525934 19549727 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
HGS DTX3L 25348397 N/A physical interaction ComPPI
IFNGR1 DTX3L 25348397 N/A physical interaction ComPPI
JAK1 DTX3L 25348397 N/A physical interaction ComPPI
PARP1 DTX3L 25348397 N/A physical interaction ComPPI
RPA1 DTX3L 25348397 N/A physical interaction ComPPI
RPA2 DTX3L 25348397 N/A physical interaction ComPPI
RPA3 DTX3L 25348397 N/A physical interaction ComPPI
SPG21 DTX3L 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
JAK2 DTX3L 25348397 N/A physical interaction ComPPI
DTX1 DTX3L 12670957 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ITCH DTX3L 25348397 N/A physical interaction ComPPI
UBE2K DTX3L 25348397 N/A physical interaction ComPPI
STAM DTX3L 25348397 N/A physical interaction ComPPI
UBE2D3 DTX3L 12670957 14525934 19549727 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
ELAVL1 DTX3L 25348397 N/A physical interaction ComPPI
UBE2H DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E1 DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DTX3L UBE2W 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DTX3L PHF7 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DTX3L PARP14 25348397 N/A physical interaction ComPPI
DTX3L NCAPG 25348397 N/A physical interaction ComPPI
DTX3L H2BC11 25348397 N/A physical interaction ComPPI
DTX3L H2AZ2 25348397 N/A physical interaction ComPPI
DTX3L G3BP1 25348397 N/A physical interaction ComPPI
DTX3L MCM7 23764002 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PPIB DTX3L 24234451 30021884 physical association cross-linking study IntAct
DTX3L H4C1 19818714 27898060 stimulant N/A OmniPath

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