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GENE：VAC14

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VAC14
FullNmae VAC14 component of PIKFYVE complex
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25507
EnsembleID ENSG00000103043
Uniprot Q08AM6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VAC14 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
VAC14 GO:0000139,GO:0005515,GO:0005783,GO:0005829,GO:0006661,GO:0007165,GO:0010008,GO:0010008,GO:0031901,GO:0031902,GO:0038023,GO:0042802,GO:0043231,GO:0070772,GO:0098830,GO:0099149

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VAC14 hsa:55697 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
VAC14 hsa:55697 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR VAC14 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 VAC14 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 VAC14 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003E1A9 VAC14 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000008DA94 VAC14 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000012A1DD VAC14 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS0000171525 VAC14 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000055BBE5 VAC14 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000055BBE5 VAC14 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000008DA94 VAC14 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000171525 VAC14 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003E1A9 VAC14 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000012A1DD VAC14 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00004214BB VAC14 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 VAC14 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000137EDE VAC14 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007F792 VAC14 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C VAC14 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 VAC14 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 VAC14 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PDE4DIP VAC14 25348397 N/A physical interaction ComPPI
RHOXF2 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRYBA1 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TP53BP1 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VENTX VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WDR83 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRK VAC14 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
BBS2 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DOCK7 VAC14 24234451 25348397 29187380 association anti bait coimmunoprecipitation ComPPI,IntAct
MVP VAC14 25348397 N/A physical interaction ComPPI
NTRK1 VAC14 25348397 N/A physical interaction ComPPI
CASP1 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MPZL1 VAC14 25348397 N/A physical interaction ComPPI
MYOZ1 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF6 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF2S1 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP2CA VAC14 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XPO1 VAC14 25348397 N/A physical interaction ComPPI
EHHADH VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EGFR VAC14 25348397 N/A physical interaction ComPPI
VAMP3 VAC14 25348397 N/A physical interaction ComPPI
CNTN2 VAC14 14525934 16767081 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
ATP2B4 VAC14 25348397 N/A physical interaction ComPPI
ATP2B2 VAC14 25348397 N/A physical interaction ComPPI
PPP6C VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
QKI VAC14 25348397 N/A physical interaction ComPPI
CD274 VAC14 25348397 N/A physical interaction ComPPI
SRPK2 VAC14 25348397 N/A physical interaction ComPPI
NOS1 VAC14 14525934 17161399 24234451 25348397 27898060 N/A experimental interaction detection,filter binding,pull down,saturation binding,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
EIF4A2 VAC14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RBFOX2 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNAI2 VAC14 25348397 N/A physical interaction ComPPI
PBLD VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIKFYVE VAC14 19037259 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MICA VAC14 25348397 N/A physical interaction ComPPI
GNB1 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NTAQ1 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
C2CD6 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PHF1 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIGLEC5 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SMUG1 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ASB13 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HNF1B VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAVS VAC14 25348397 N/A physical interaction ComPPI
PRAF2 VAC14 25348397 N/A physical interaction ComPPI
VAC14 APP 25348397 N/A physical interaction ComPPI
VAC14 TCEANC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VAC14 BSG 25348397 N/A physical interaction ComPPI
VAC14 ZMPSTE24 25348397 N/A physical interaction ComPPI
VAC14 RAB21 25348397 N/A physical interaction ComPPI
VAC14 GINS3 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VAC14 WRAP53 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAC14 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAC14 RNASEH2C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAC14 RIPPLY1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAC14 KRT82 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAC14 GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAC14 SEC16A 24234451 25348397 29187380 association anti bait coimmunoprecipitation ComPPI,IntAct
VAC14 STING1 24234451 25348397 29251827 association anti bait coimmunoprecipitation ComPPI,IntAct
CD209 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLMAP VAC14 25348397 N/A physical interaction ComPPI
PELI1 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GABPB2 VAC14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VAC14 AGTR1 24234451 28298427 physical association anti tag coimmunoprecipitation IntAct

Visualization










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