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GENE：AMOTL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AMOTL2
FullNmae angiomotin like 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17812
EnsembleID ENSG00000114019
Uniprot Q9Y2J4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AMOTL2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AMOTL2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AMOTL2 GO:0001525,GO:0003365,GO:0005515,GO:0005829,GO:0005886,GO:0005923,GO:0016055,GO:0030036,GO:0030334,GO:0031410,GO:0035329,GO:0055037

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AMOTL2 hsa:51421 path:hsa04530 Tight junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR AMOTL2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 AMOTL2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 AMOTL2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 AMOTL2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 AMOTL2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 AMOTL2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 AMOTL2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF AMOTL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 AMOTL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 AMOTL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A AMOTL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF AMOTL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001B341F AMOTL2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00003AD231 AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075BC91 AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 AMOTL2 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA AMOTL2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000EF0B AMOTL2 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 AMOTL2 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D50C AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF AMOTL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A AMOTL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 AMOTL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004818BD AMOTL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF AMOTL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000001C659 AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005F305A AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000047944F AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 AMOTL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000058863C AMOTL2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B0F6 AMOTL2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000009265 AMOTL2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000010BD8D AMOTL2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MTOR AMOTL2 22135298 phosphorylation N/A PhosphoSite
LATS2 AMOTL2 22135298 phosphorylation N/A PhosphoSite
FGFR1 AMOTL2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MFAP1 AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMO4 AMOTL2 25348397 N/A physical interaction ComPPI
BYSL AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CHCHD3 AMOTL2 25348397 N/A physical interaction ComPPI
GOLGA2 AMOTL2 25348397 N/A physical interaction ComPPI
GNG5 AMOTL2 25348397 N/A physical interaction ComPPI
MORF4L2 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMARCE1 AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAGOHB AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
GCC1 AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DAXX AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL1 AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF40 AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZBED1 AMOTL2 25348397 N/A physical interaction ComPPI
KRT19 AMOTL2 25348397 N/A physical interaction ComPPI
YES1 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RALBP1 AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAA2 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDC80 AMOTL2 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PALS1 AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR2 AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KRT38 AMOTL2 25348397 N/A physical interaction ComPPI
KRT20 AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PSMC3 AMOTL2 24234451 24255178 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BFSP2 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTM5 AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP4-2 AMOTL2 25348397 N/A physical interaction ComPPI
MAGEA4 AMOTL2 25348397 N/A physical interaction ComPPI
AMOT AMOTL2 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GNG11 AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCDC185 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDR2 AMOTL2 25348397 N/A physical interaction ComPPI
RASSF5 AMOTL2 25348397 N/A physical interaction ComPPI
TP53BP2 AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT31 AMOTL2 25348397 N/A physical interaction ComPPI
SPAG5 AMOTL2 25348397 N/A physical interaction ComPPI
NF2 AMOTL2 21481793 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MPDZ AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPP1 AMOTL2 25348397 N/A physical interaction ComPPI
THRA AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYC AMOTL2 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PARD3 AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BLZF1 AMOTL2 25348397 N/A physical interaction ComPPI
XPO1 AMOTL2 25348397 N/A physical interaction ComPPI
TRAF2 AMOTL2 25348397 N/A physical interaction ComPPI
RNF8 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZBTB16 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SP100 AMOTL2 25348397 N/A physical interaction ComPPI
SOX2 AMOTL2 25348397 N/A physical interaction ComPPI
YAP1 AMOTL2 24234451 24255178 24366813 25348397 25751139 colocalization,association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
COPS6 AMOTL2 25348397 N/A physical interaction ComPPI
LIN7C AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SVIL AMOTL2 14525934 16880273 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
CDC37 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNRPD2 AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD51D AMOTL2 21516116 24234451 25348397 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
MPP1 AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
MTNR1A AMOTL2 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
TRIM27 AMOTL2 25348397 N/A physical interaction ComPPI
BRMS1L AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NFIL3 AMOTL2 21516116 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HECW2 AMOTL2 25348397 N/A physical interaction ComPPI
KRT1 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PATJ AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO5B AMOTL2 25348397 N/A physical interaction ComPPI
MAD1L1 AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CARD9 AMOTL2 25348397 N/A physical interaction ComPPI
DDIT3 AMOTL2 25348397 N/A physical interaction ComPPI
PRPF18 AMOTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF4E2 AMOTL2 25348397 N/A physical interaction ComPPI
MTMR6 AMOTL2 25348397 N/A physical interaction ComPPI
LATS2 AMOTL2 25348397 N/A physical interaction ComPPI
NME2 AMOTL2 24234451 24255178 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NTAQ1 AMOTL2 25348397 N/A physical interaction ComPPI
KRT15 AMOTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AMOTL2 TRAPPC14 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AMOTL2 PSMD9 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AMOTL2 TRAPPC10 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AMOTL2 TRAPPC3 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AMOTL2 TRAPPC9 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AMOTL2 KRT13 25348397 N/A physical interaction ComPPI
AMOTL2 TMCC2 25348397 N/A physical interaction ComPPI
AMOTL2 CYTH4 25348397 N/A physical interaction ComPPI
AMOTL2 CCHCR1 25348397 N/A physical interaction ComPPI
AMOTL2 FAM184A 25348397 N/A physical interaction ComPPI
AMOTL2 ZGPAT 25348397 N/A physical interaction ComPPI
AMOTL2 SH3RF2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 USP9X 25348397 N/A physical interaction ComPPI
AMOTL2 HTATIP2 25348397 N/A physical interaction ComPPI
AMOTL2 TCEA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 DZIP1L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 RASAL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 FCRL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 TSGA10IP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 CWF19L2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 KIF9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 CINP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 NME7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 L3MBTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF20 AMOTL2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 AMOTL2 14525934 16189514 24234451 physical association two hybrid pooling approach,two hybrid HPRD,IntAct
ERP29 AMOTL2 24234451 30021884 physical association cross-linking study IntAct
FGFR1 AMOTL2 21937427 27898060 N/A N/A OmniPath
LATS2 AMOTL2 21832154 24225952 24255178 26598551 27898060 N/A N/A OmniPath

Visualization










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