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GENE：DHCR7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DHCR7
FullNmae 7-dehydrocholesterol reductase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2860
EnsembleID ENSG00000172893
Uniprot Q9UBM7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DHCR7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DHCR7 GO:0005515,GO:0005640,GO:0005783,GO:0005789,GO:0006695,GO:0006695,GO:0009918,GO:0016020,GO:0016132,GO:0033489,GO:0033490,GO:0047598,GO:0047598,GO:0047598,GO:0050661

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DHCR7 hsa:1717 path:hsa00100 Steroid biosynthesis - Homo sapiens (human)
DHCR7 hsa:1717 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FADS1 DHCR7 17353931 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 DHCR7 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
GATA2 DHCR7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 DHCR7 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A DHCR7 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXA1 DHCR7 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DHCR7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000048BA36 DHCR7 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000237AF9 DHCR7 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 DHCR7 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000239117 DHCR7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001EFEC1 DHCR7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 DHCR7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000033B91D DHCR7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005A8A8D DHCR7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 DHCR7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F DHCR7 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CYP51A1 DHCR7 25361965 interaction type N/A PTMCode2
DHCR7 CYP51A1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ISG15 DHCR7 24234451 25348397 26259872 association pull down ComPPI,IntAct
KEAP1 DHCR7 25348397 N/A physical interaction ComPPI
ERBB2 DHCR7 24189400 24234451 25348397 association tandem affinity purification ComPPI,IntAct
UBC DHCR7 25348397 N/A physical interaction ComPPI
PTPN1 DHCR7 25348397 N/A physical interaction ComPPI
ILK DHCR7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PTPN5 DHCR7 25348397 N/A physical interaction ComPPI
TNIK DHCR7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NDN DHCR7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MMS19 DHCR7 25348397 N/A physical interaction ComPPI
CUL7 DHCR7 25348397 N/A physical interaction ComPPI
ESRRB DHCR7 25348397 N/A physical interaction ComPPI
TGOLN2 DHCR7 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 DHCR7 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AGO2 DHCR7 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RRP1B DHCR7 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TOR1A DHCR7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CYLD DHCR7 25348397 N/A physical interaction ComPPI
ACP6 DHCR7 25348397 N/A physical interaction ComPPI
FADS1 DHCR7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DHCR7 STAU1 25348397 N/A physical interaction ComPPI
DHCR7 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DHCR7 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DHCR7 LTN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHCR7 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
DHCR7 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization










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