Gene Information gene info

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GENE：DGKE

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DGKE
FullNmae diacylglycerol kinase epsilon
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2852
EnsembleID ENSG00000153933
Uniprot P52429

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DGKE immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DGKE GO:0004143,GO:0004143,GO:0005524,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006654,GO:0006661,GO:0007205,GO:0016020,GO:0016020,GO:0016301,GO:0030168,GO:0046339,GO:0046834,GO:0046872,GO:0050804,GO:0098978

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DGKE hsa:8526 path:hsa00561 Glycerolipid metabolism - Homo sapiens (human)
DGKE hsa:8526 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
DGKE hsa:8526 path:hsa01100 Metabolic pathways - Homo sapiens (human)
DGKE hsa:8526 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)
DGKE hsa:8526 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
DGKE hsa:8526 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 DGKE 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DGKE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DGKE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DGKE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 DGKE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 DGKE N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 DGKE 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000D2680 DGKE 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE DGKE 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 DGKE 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001D6605 DGKE 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD DGKE 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000024DFCE DGKE 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 DGKE 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 DGKE 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 DGKE 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 DGKE 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED DGKE 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003E2232 DGKE 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000018D2BE DGKE 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SET DGKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN5 DGKE 25348397 N/A physical interaction ComPPI
PDHA1 DGKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ARRB1 DGKE 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARRB2 DGKE 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDC DGKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PAICS DGKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL44 DGKE 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NUF2 DGKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct

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