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GENE：ARHGAP17

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARHGAP17
FullNmae Rho GTPase activating protein 17
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18239
EnsembleID ENSG00000140750
Uniprot Q68EM7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARHGAP17 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARHGAP17 GO:0005096,GO:0005515,GO:0005622,GO:0005829,GO:0005829,GO:0005886,GO:0005923,GO:0007015,GO:0007165,GO:0017124,GO:0017156,GO:0032956,GO:0035020

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARHGAP17 hsa:55114 path:hsa04530 Tight junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ARHGAP17 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ARHGAP17 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ARHGAP17 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C ARHGAP17 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ARHGAP17 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 ARHGAP17 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000005481D ARHGAP17 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD ARHGAP17 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 ARHGAP17 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA ARHGAP17 22135298 phosphorylation N/A PhosphoSite
PACSIN1 ARHGAP17 25361965 interaction type N/A PTMCode2
ARHGAP17 PACSIN1 25361965 interaction type N/A PTMCode2
ARHGAP17 CDC42 25361965 interaction type N/A PTMCode2
CDC42 ARHGAP17 25361965 interaction type N/A PTMCode2
ARHGAP17 RAC1 25361965 interaction type N/A PTMCode2
RAC1 ARHGAP17 25361965 interaction type N/A PTMCode2
PIK3R1 ARHGAP17 25361965 interaction type N/A PTMCode2
ARHGAP17 PIK3R1 25361965 interaction type N/A PTMCode2
SLC9A3R1 ARHGAP17 25361965 interaction type N/A PTMCode2
ARHGAP17 SLC9A3R1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DDX6 ARHGAP17 25348397 N/A physical interaction ComPPI
CDC42 ARHGAP17 25348397 N/A physical interaction ComPPI
PALS1 ARHGAP17 25348397 N/A physical interaction ComPPI
SH3GLB1 ARHGAP17 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SH3KBP1 ARHGAP17 25348397 N/A physical interaction ComPPI
AMOT ARHGAP17 21481793 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
VCP ARHGAP17 25348397 N/A physical interaction ComPPI
PRKCI ARHGAP17 25348397 N/A physical interaction ComPPI
ALDOC ARHGAP17 25348397 N/A physical interaction ComPPI
ARHGAP17 TRIP10 11431473 14525934 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ARHGAP17 SRC 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 CRK 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 GRB2 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 PIK3R1 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 LCK 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 PACSIN1 11431473 14525934 20936779 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro ComPPI,HPRD,IntAct
ARHGAP17 FNBP1 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 CTTN 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 BTK 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGAP17 PACSIN2 25348397 N/A physical interaction ComPPI
ARHGAP17 ABL1 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ARHGAP17 RAC1 25348397 N/A physical interaction ComPPI
ARHGAP17 DNMBP 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ARHGAP17 ARRB2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARHGAP17 PATJ 25348397 N/A physical interaction ComPPI
ARHGAP17 CD2AP 25348397 N/A physical interaction ComPPI
ARHGAP17 CAPZA1 25348397 N/A physical interaction ComPPI
ARHGAP17 CAPZB 25348397 N/A physical interaction ComPPI
ARHGAP17 PARD3 25348397 N/A physical interaction ComPPI
ARHGAP17 PARD6A 25348397 N/A physical interaction ComPPI
ARHGAP17 APP 25348397 N/A physical interaction ComPPI
ARHGAP17 FMNL1 25348397 N/A physical interaction ComPPI
ARHGAP17 NXF1 25348397 N/A physical interaction ComPPI
ARHGAP17 ACTR3 25348397 N/A physical interaction ComPPI
ARHGAP17 CHMP7 25348397 N/A physical interaction ComPPI
ARHGAP17 COMMD2 25348397 N/A physical interaction ComPPI
ARHGAP17 COMMD4 25348397 N/A physical interaction ComPPI
ARHGAP17 STXBP1 25348397 N/A physical interaction ComPPI
ARHGAP17 ARPC2 25348397 N/A physical interaction ComPPI
ARHGAP17 NLRP3 25348397 N/A physical interaction ComPPI
ARHGAP17 OPA1 25348397 N/A physical interaction ComPPI
ARHGAP17 NTRK1 25348397 N/A physical interaction ComPPI
ARHGAP17 EWSR1 25348397 N/A physical interaction ComPPI
ARHGAP17 ARHGAP44 25348397 N/A physical interaction ComPPI
ARHGAP17 PDZK1P1 25348397 N/A physical interaction ComPPI
ARHGAP17 PDZK1 25348397 N/A physical interaction ComPPI
ARHGAP17 SH3BP1 25348397 N/A physical interaction ComPPI
ARHGAP17 KLC1 25348397 N/A physical interaction ComPPI
ARHGAP17 COA8 25348397 N/A physical interaction ComPPI
ARHGAP17 GALNT16 25348397 N/A physical interaction ComPPI
ARHGAP17 SLC9A3R1 11285285 24234451 25348397 N/A filter binding ComPPI,IntAct
ARHGAP17 NF2 25348397 N/A anti tag coimmunoprecipitation ComPPI
ARHGAP17 HSCB 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4EBP2 ARHGAP17 25348397 N/A physical interaction ComPPI
CDK9 ARHGAP17 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B3310 ARHGAP17 27087310 direct interaction,inhibition N/A NPInter

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