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GENE：CYFIP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CYFIP2
FullNmae cytoplasmic FMR1 interacting protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13760
EnsembleID ENSG00000055163
Uniprot Q96F07

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CYFIP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CYFIP2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CYFIP2 GO:0000902,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006915,GO:0006915,GO:0007411,GO:0016020,GO:0030031,GO:0030833,GO:0031209,GO:0031267,GO:0043005,GO:0045202,GO:0045202,GO:0045862,GO:0048471,GO:0051388,GO:0070062,GO:0097202,GO:0097202,GO:0097484,GO:0098609

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CYFIP2 hsa:26999 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
CYFIP2 hsa:26999 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
CYFIP2 hsa:26999 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RAC1 CYFIP2 12181570 26192618 interaction type N/A ACSN
CYFIP2 WASF1 12181570 16212495 16702231 26192618 9843499 interaction type N/A ACSN
CYFIP2 BNIP2 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR CYFIP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CYFIP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 CYFIP2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CYFIP2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CYFIP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CYFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXD3 CYFIP2 23058321 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CYFIP2 15856024 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 CYFIP2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D CYFIP2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003AAF6D CYFIP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000237AF9 CYFIP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001919B0 CYFIP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001B0D1E CYFIP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000042B108 CYFIP2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NCK1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 NCK1 25361965 interaction type N/A PTMCode2
NCKAP1L CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 NCKAP1L 25361965 interaction type N/A PTMCode2
CYFIP2 WASF2 25361965 interaction type N/A PTMCode2
WASF2 CYFIP2 25361965 interaction type N/A PTMCode2
ABI1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 ABI1 25361965 interaction type N/A PTMCode2
FXR1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 FXR1 25361965 interaction type N/A PTMCode2
NCKAP1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 NCKAP1 25361965 interaction type N/A PTMCode2
FMR1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 FMR1 25361965 interaction type N/A PTMCode2
FXR2 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 FXR2 25361965 interaction type N/A PTMCode2
WASF1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 WASF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 CYFIP2 25348397 N/A physical interaction ComPPI
HSPA8 CYFIP2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FXR2 CYFIP2 11438699 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,IntAct
PACSIN3 CYFIP2 25348397 N/A physical interaction ComPPI
VASP CYFIP2 25348397 N/A physical interaction ComPPI
YWHAG CYFIP2 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CCDC22 CYFIP2 25348397 N/A physical interaction ComPPI
SMAD4 CYFIP2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZC3H12A CYFIP2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LHX4 CYFIP2 25348397 N/A physical interaction ComPPI
PACSIN1 CYFIP2 25348397 N/A physical interaction ComPPI
NCK1 CYFIP2 14525934 25348397 8605018 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
UBXN11 CYFIP2 25348397 N/A physical interaction ComPPI
CBLC CYFIP2 25348397 N/A physical interaction ComPPI
GRB2 CYFIP2 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLG CYFIP2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
YWHAB CYFIP2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAZ CYFIP2 14676191 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 CYFIP2 25348397 N/A physical interaction ComPPI
PRPF40A CYFIP2 25348397 N/A physical interaction ComPPI
WASF1 CYFIP2 12181570 14525934 16862120 25348397 8605018 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
APBB1 CYFIP2 25348397 N/A physical interaction ComPPI
MARK4 CYFIP2 25348397 N/A physical interaction ComPPI
ANG CYFIP2 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
HOMER3 CYFIP2 25348397 N/A physical interaction ComPPI
ABI1 CYFIP2 14525934 15048123 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
ABI3 CYFIP2 14525934 17101133 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
YWHAH CYFIP2 14676191 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABI2 CYFIP2 25348397 N/A physical interaction ComPPI
PTPRE CYFIP2 25348397 N/A physical interaction ComPPI
WWOX CYFIP2 25348397 N/A physical interaction ComPPI
TCERG1 CYFIP2 25348397 N/A physical interaction ComPPI
FXR1 CYFIP2 11438699 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
FMR1 CYFIP2 11438699 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
CYFIP1 CYFIP2 11438699 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
CYFIP2 NCKAP1 14525934 15048123 16055720 24234451 25348397 8605018 physical association experimental interaction detection,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
CYFIP2 DNMBP 14506234 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CYFIP2 BRK1 14525934 25348397 8605018 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CYFIP2 PACSIN2 25348397 N/A physical interaction ComPPI
CYFIP2 LPA 25348397 N/A physical interaction ComPPI
CYFIP2 BIRC3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CYFIP2 GAS7 16055720 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
CYFIP2 STAU1 25348397 N/A physical interaction ComPPI
CYFIP2 ZNF511 25348397 N/A physical interaction ComPPI
CYFIP2 DTNBP1 25348397 N/A physical interaction ComPPI
CYFIP2 BAIAP2 25348397 N/A physical interaction ComPPI
CYFIP2 HSPB9 25348397 N/A physical interaction ComPPI
CYFIP2 NCKAP1L 25348397 N/A physical interaction ComPPI
CYFIP2 WASF2 14525934 15048123 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
CYFIP2 WASF3 25348397 N/A physical interaction ComPPI
CYFIP2 TCF4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CYFIP2 AMZ1 25348397 N/A physical interaction ComPPI
CYFIP2 IKBIP 25348397 N/A physical interaction ComPPI
CYFIP2 NHSL2 25348397 N/A physical interaction ComPPI
CYFIP2 TIMM50 25348397 N/A physical interaction ComPPI
CYFIP2 CGB2 25348397 N/A physical interaction ComPPI
CYFIP2 NYAP1 25348397 N/A physical interaction ComPPI
CYFIP2 NYAP2 25348397 N/A physical interaction ComPPI
CYFIP2 MYO16 25348397 N/A physical interaction ComPPI
CYFIP2 LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
CYFIP2 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CYFIP2 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CYFIP2 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CYFIP2 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
OXTR CYFIP2 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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