Gene Information gene info

GENE:EIF3G

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF3G
FullNmae eukaryotic translation initiation factor 3 subunit G
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3274
EnsembleID ENSG00000130811
Uniprot O75821

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF3G immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF3G GO:0001732,GO:0003723,GO:0003723,GO:0003743,GO:0003743,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0005852,GO:0005852,GO:0006413,GO:0006413,GO:0016282,GO:0033290,GO:0048471,GO:0075525

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EIF3D EIF3G 18628297 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP EIF3G 21832049 23180781 physical association protein array InnateDB
EIF3G EPB41 10887144 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 EIF3G 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EIF3G 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 EIF3G 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 EIF3G 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EIF3G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EIF3G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EIF3G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 EIF3G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 EIF3G 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 EIF3G 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000048BA36 EIF3G 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 EIF3G 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RPS5 EIF3G 25361965 interaction type N/A PTMCode2
EIF3G RPS5 25361965 interaction type N/A PTMCode2
EIF3D EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EIF3D 25361965 interaction type N/A PTMCode2
EIF3G EIF3J 25361965 interaction type N/A PTMCode2
EIF3J EIF3G 25361965 interaction type N/A PTMCode2
EIF3G AIFM1 25361965 interaction type N/A PTMCode2
AIFM1 EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EPB41 25361965 interaction type N/A PTMCode2
EPB41 EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EIF3F 25361965 interaction type N/A PTMCode2
EIF3F EIF3G 25361965 interaction type N/A PTMCode2
EIF3G RPS14 25361965 interaction type N/A PTMCode2
RPS14 EIF3G 25361965 interaction type N/A PTMCode2
EIF3G RPS15A 25361965 interaction type N/A PTMCode2
RPS15A EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EIF3C 25361965 interaction type N/A PTMCode2
EIF3C EIF3G 25361965 interaction type N/A PTMCode2
EIF3G RPS10 25361965 interaction type N/A PTMCode2
RPS10 EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EIF3B 25361965 interaction type N/A PTMCode2
EIF3B EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EIF3A 25361965 interaction type N/A PTMCode2
EIF3A EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EIF3I 25361965 interaction type N/A PTMCode2
EIF3I EIF3G 25361965 interaction type N/A PTMCode2
EIF3G USP3 25361965 interaction type N/A PTMCode2
USP3 EIF3G 25361965 interaction type N/A PTMCode2
EIF3G RPS6 25361965 interaction type N/A PTMCode2
RPS6 EIF3G 25361965 interaction type N/A PTMCode2
EIF3G RPS8 25361965 interaction type N/A PTMCode2
RPS8 EIF3G 25361965 interaction type N/A PTMCode2
EIF3E EIF3G 25361965 interaction type N/A PTMCode2
EIF3G EIF3E 25361965 interaction type N/A PTMCode2
FBL EIF3G 25361965 interaction type N/A PTMCode2
EIF3G FBL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 EIF3G 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GOLGA2 EIF3G 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF3G EIF5 14525934 25348397 9973622 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EIF3G EIF3A 14525934 18599441 24234451 24396066 25348397 9822659 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,mass spectrometry studies of complexes,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EIF3G EIF3H 14525934 19615732 24234451 25348397 9822659 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EIF3G EIF3D 14525934 25348397 9822659 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF3G EIF3C 14525934 18599441 24234451 24396066 25348397 9822659 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,mass spectrometry studies of complexes,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EIF3G EIF3B 14525934 14688252 18599441 18628297 24234451 24396066 25348397 30021884 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,experimental interaction detection,mass spectrometry studies of complexes,physical interaction,in vivo ComPPI,HPRD,IntAct
EIF3G PALS2 14525934 15231747 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
EIF3G EIF3K 14519125 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
EIF3G MPHOSPH6 14525934 15231747 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
EIF3G AIFM1 14525934 17094969 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,two hybrid array,imaging technique,in vitro,two hybrid ComPPI,HPRD,IntAct
EIF3G EIF1B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3G EPB41 10887144 25348397 27898060 N/A physical interaction ComPPI,OmniPath
EIF3G EIF3F 25348397 N/A physical interaction ComPPI
EIF3G USP3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3G GADD45G 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3G SNCA 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3G TK1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3G SMN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3G PKN2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3G ACD 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
EIF3G POT1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
EIF3G CUL3 25348397 N/A physical interaction ComPPI
EIF3G EIF3E 25348397 N/A physical interaction ComPPI
EIF3G APP 25348397 N/A physical interaction ComPPI
EIF3G EIF3I 17094969 18599441 24234451 25348397 physical association two hybrid,mass spectrometry studies of complexes,physical interaction,two hybrid array ComPPI,IntAct
EIF3G EIF3L 25348397 N/A physical interaction ComPPI
EIF3G EIF3M 25348397 N/A physical interaction ComPPI
EIF3G DDX3X 18628297 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3G PAN2 25348397 N/A physical interaction ComPPI
EIF3G CD81 25348397 N/A physical interaction ComPPI
EIF3G IGSF8 25348397 N/A physical interaction ComPPI
EIF3G ICAM1 25348397 N/A physical interaction ComPPI
EIF3G NPM1 25348397 N/A physical interaction ComPPI
EIF3G DYNC1I2 25348397 N/A physical interaction ComPPI
EIF3G NCL 25348397 N/A physical interaction ComPPI
EIF3G FAM9B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF3G PAIP1 24234451 24396066 25348397 association pull down,physical interaction ComPPI,IntAct
EIF3G EIF1 25348397 N/A physical interaction ComPPI
EIF3G EIF3CL 25348397 N/A physical interaction ComPPI
EIF3G MSI2 25348397 N/A physical interaction ComPPI
EIF3G MTHFD1 25348397 N/A physical interaction ComPPI
EIF3G SFN 25348397 N/A physical interaction ComPPI
EIF3G NTRK1 25348397 N/A physical interaction ComPPI
EIF3G HERC2 24234451 25348397 29426014 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3G HERC2P3 25348397 N/A physical interaction ComPPI
EIF3G PRKAG1 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3G AHSA1 25348397 N/A physical interaction ComPPI
EIF3G RPL10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3G CERKL 25348397 N/A physical interaction ComPPI
EIF3G CYLD 25348397 N/A physical interaction ComPPI
EIF3G DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EIF3G G3BP1 25348397 N/A physical interaction ComPPI
EIF3G LMNA 25348397 N/A physical interaction ComPPI
EIF3G BRCA1 25348397 N/A physical interaction ComPPI
EIF3G EIF3J 14688252 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF3G ARF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3G SNW1 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3G CDC5L 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3G UVRAG 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF3G PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3G PELO 20406461 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,bimolecular fluorescence complementation ComPPI,IntAct
EIF3G EIF3G 14525934 9822659 N/A experimental interaction detection HPRD
EIF3G MIF4GD 23804756 24234451 physical association two hybrid,pull down IntAct
EIF3G CAPN11 24234451 30021884 physical association cross-linking study IntAct
TPT1 EIF3G 24234451 27607350 association anti bait coimmunoprecipitation IntAct

Source Target Pmid Interactiontype Methods Database
URS00009BBBB8 EIF3G 27087310 direct interaction,inhibition N/A NPInter

Visualization