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GENE：MBP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MBP
FullNmae myelin basic protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6925
EnsembleID ENSG00000197971
Uniprot P02686

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MBP immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MBP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MBP GO:0000165,GO:0002020,GO:0005515,GO:0005516,GO:0005634,GO:0005829,GO:0005886,GO:0006955,GO:0007268,GO:0007417,GO:0007605,GO:0008366,GO:0009636,GO:0009986,GO:0019911,GO:0021762,GO:0032755,GO:0032991,GO:0033269,GO:0034115,GO:0035633,GO:0042552,GO:0043025,GO:0043209,GO:0043218,GO:0045202,GO:0061024,GO:0071944,GO:1904685,GO:2000343

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MBP SQSTM1 14702098 23180781 physical association pull down InnateDB
APP MBP 16049941 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR MBP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MBP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C MBP 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MBP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 MBP 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXM1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TBP MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NF1 MBP 9765312 trascriptional regulation,stimulation inferred by curator TFlink
NFIB MBP 1699939 trascriptional regulation,stimulation inferred by curator TFlink
SOX10 MBP 11734543 trascriptional regulation,stimulation inferred by curator TFlink
NFIC MBP N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007340 MBP 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK3 MBP 22135298 phosphorylation N/A PhosphoSite
MAPK1 MBP 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
STK16 MBP 25348397 N/A in vitro,in vivo ComPPI
TRAF6 MBP 10346818 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CALM1 MBP 25348397 N/A isothermal titration calorimetry,nuclear magnetic resonance,physical interaction ComPPI
RAN MBP 12101123 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ATXN1 MBP 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PAK1 MBP 25348397 N/A in vitro ComPPI
MMP7 MBP 14525934 25348397 27898060 8786845 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
MAPK1 MBP 12760422 14525934 15380617 25348397 9792705 N/A experimental interaction detection,physical interaction,protein kinase assay,in vitro ComPPI,HPRD
MAPK8 MBP 25348397 N/A physical interaction ComPPI
PRKCA MBP 14525934 2413024 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRKCD MBP 11964256 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRKDC MBP 25348397 N/A physical interaction ComPPI
MAPK3 MBP 10339476 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAPKAPK5 MBP 14525934 25348397 9628874 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK14 MBP 14525934 15728454 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PKN1 MBP 25348397 N/A physical interaction ComPPI
PRKACA MBP 14525934 2413024 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TRPM7 MBP 14525934 14594813 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRMT1 MBP 14525934 25348397 27898060 4924231 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
APTX MBP 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PTPRA MBP 25348397 N/A physical interaction ComPPI
MAP3K5 MBP 25348397 N/A physical interaction ComPPI
PRKCB MBP 25348397 N/A physical interaction ComPPI
CLK1 MBP 14525934 25348397 8798720 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK13 MBP 14525934 25348397 9207191 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRMT5 MBP 11152681 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
HNRNPL MBP 25348397 N/A physical interaction ComPPI
DYRK1B MBP 10910078 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCZ MBP 10383403 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PPP2R5C MBP 25348397 N/A physical interaction ComPPI
IRAK1 MBP 10346818 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SQSTM1 MBP 25348397 N/A physical interaction ComPPI
RXRB MBP 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SRPK1 MBP 10390541 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RPS6KA5 MBP 14525934 25348397 9873047 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MELK MBP 14525934 16216881 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MBP MAPK11 25348397 N/A physical interaction,in vitro ComPPI
MBP HLA-DRA 14525934 25348397 27898060 9782128 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
MBP MAG 12237860 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MBP PLP1 14525934 2467009 25348397 6083474 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MBP STK4 14525934 25348397 7665586 N/A experimental interaction detection,in vitro ComPPI,HPRD
MBP CTDSP1 14525934 14743429 24234451 25348397 25416956 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
MBP STK26 11641781 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MBP RTN4 12377379 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MBP STK39 10980603 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MBP BMP2K 11500515 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MBP TLK2 25348397 N/A in vitro ComPPI
MBP CDK12 11683387 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MBP NEK9 11864968 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MBP TLK1 25348397 N/A physical interaction,in vitro ComPPI
MBP MICU2 11124993 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
MBP MAPK15 11875070 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MBP TSSK6 25348397 N/A physical interaction ComPPI
MBP IRAK4 25348397 N/A physical interaction ComPPI
MBP LIMK1 25348397 N/A physical interaction ComPPI
MBP LIMK2 25348397 N/A physical interaction ComPPI
MBP TBK1 25348397 N/A physical interaction ComPPI
MBP IKBKE 25348397 N/A physical interaction ComPPI
MBP STK3 25348397 N/A physical interaction ComPPI
MBP ATN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MBP LRRK2 16269541 17260967 17584768 17706965 19826009 21806997 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MBP MAPK12 25348397 N/A physical interaction ComPPI
MBP CDK1 25348397 N/A physical interaction ComPPI
MBP CDK5 25348397 N/A physical interaction ComPPI
MBP RPS6KA6 25348397 N/A physical interaction ComPPI
MBP DDX58 25348397 N/A physical interaction ComPPI
MBP CDK7 25348397 N/A physical interaction ComPPI
MBP CDK8 25348397 N/A physical interaction ComPPI
MBP CDK9 25348397 N/A physical interaction ComPPI
MBP HIPK2 25348397 N/A physical interaction ComPPI
MBP ULK1 25348397 N/A physical interaction ComPPI
MBP MAP3K3 25348397 N/A physical interaction ComPPI
MBP ABL1 25348397 N/A physical interaction ComPPI
MBP MYH6 25348397 N/A physical interaction ComPPI
MBP MAP3K1 25348397 N/A physical interaction ComPPI
MBP CTDSPL 25348397 N/A physical interaction ComPPI
MBP NLN 25348397 N/A physical interaction ComPPI
MBP IDE 25348397 N/A physical interaction ComPPI
MBP DDX54 25348397 N/A physical interaction ComPPI
MBP PBK 10779557 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
MBP APP 16049941 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MBP HLA-DRB1 21131964 23260142 24234451 25348397 association,physical association fluorescence polarization spectroscopy ComPPI,IntAct
MBP HLA-DMA 21131964 24234451 25348397 association surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
MBP PDGFRL 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PRKCI MBP 10383403 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MKNK1 MBP 14525934 9155018 N/A experimental interaction detection HPRD
MBP ADRB2 24234451 28298427 physical association bioluminescence resonance energy transfer,ubiquitin reconstruction IntAct
MBP CCR1 24234451 28298427 physical association bioluminescence resonance energy transfer,ubiquitin reconstruction IntAct
PTAFR MBP 24234451 28298427 physical association bioluminescence resonance energy transfer,ubiquitin reconstruction IntAct
PTPN13 MBP 27898060 7929060 N/A N/A OmniPath
PRKCA MBP 10460230 2413024 27898060 stimulant N/A OmniPath
PRKD1 MBP 17939756 27898060 stimulant N/A OmniPath
MAPK3 MBP 10339476 11570821 14530346 15544353 16401070 17906618 1939237 19910486 27898060 9395235 inhibition N/A OmniPath
PPP1CB MBP 16585947 27898060 8617739 N/A N/A OmniPath
DUSP22 MBP 12204117 27898060 N/A N/A OmniPath
PPP1CA MBP 16585947 27898060 8617739 N/A N/A OmniPath
MAPK1 MBP 10371216 10958680 11258664 11570821 11983899 12588875 12760422 14530346 15380617 16401070 17906618 1939237 22778266 27898060 8846788 9792705 inhibition N/A OmniPath
PAK1 MBP 11435472 12374744 14579272 27898060 N/A N/A OmniPath
PPP2CA MBP 10866685 16895907 27898060 9644267 N/A N/A OmniPath
PPP1CC MBP 16585947 27898060 8617739 N/A N/A OmniPath
UHMK1 MBP 10880969 16401070 27898060 inhibition N/A OmniPath
PPP6C MBP 16895907 27898060 N/A N/A OmniPath
PPP2CB MBP 10866685 16895907 27898060 9644267 N/A N/A OmniPath
DUSP11 MBP 10347225 27898060 N/A N/A OmniPath
DUSP23 MBP 15281913 27898060 N/A N/A OmniPath
DUSP13 MBP 10585869 27898060 N/A N/A OmniPath

Visualization










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