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GENE：PTPRM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPRM
FullNmae protein tyrosine phosphatase receptor type M
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9675
EnsembleID ENSG00000173482
Uniprot P28827

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPRM immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPRM GO:0001937,GO:0004725,GO:0004725,GO:0005001,GO:0005515,GO:0005737,GO:0005886,GO:0005886,GO:0005911,GO:0005912,GO:0006470,GO:0006470,GO:0007156,GO:0007165,GO:0009410,GO:0010596,GO:0010842,GO:0016525,GO:0016791,GO:0030027,GO:0031175,GO:0031175,GO:0031290,GO:0042802,GO:0043232,GO:0045296,GO:0048471,GO:0051220

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTPRM hsa:5797 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)
PTPRM hsa:5797 path:hsa04520 Adherens junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PTPRM RACK1 11801604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PTPRM 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TP73 PTPRM 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PTPRM 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PTPRM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PTPRM 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000016914 PTPRM 23497265 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00005E6F45 PTPRM 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 PTPRM 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 PTPRM 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 PTPRM 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB PTPRM 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PTPRM CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 PTPRM 25361965 interaction type N/A PTMCode2
PTPRM CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 PTPRM 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CTNND1 PTPRM 10753936 14525934 15588985 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RACK1 PTPRM 11278757 11801604 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
LCK PTPRM 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CDH1 PTPRM 15588985 25348397 27898060 7642713 9531566 N/A physical interaction,biochemical,in vitro,in vivo ComPPI,OmniPath
PTPRA PTPRM 10777529 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
PTPRM PPFIBP1 25348397 N/A in vitro ComPPI
PTPRM CTNNB1 14525934 15588985 25348397 7642713 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPRM PCSK5 14525934 25348397 27898060 8620001 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PTPRM PTPRS 12376545 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPRM DTNBP1 25348397 N/A physical interaction ComPPI
PTPRM LMTK2 25348397 N/A physical interaction ComPPI
PTPRM EHD4 25348397 N/A physical interaction ComPPI
PTPRM CDC42BPA 25348397 N/A physical interaction ComPPI
PTPRM NHSL1 25348397 N/A physical interaction ComPPI
PTPRM TRIM25 25348397 N/A physical interaction ComPPI
PTPRM PTPRM 10809770 12376545 14525934 15978577 24234451 7961788 8394372 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,tox-r dimerization assay,two hybrid HPRD,IntAct
PTPRK PTPRM 14525934 27898060 7782276 N/A experimental interaction detection HPRD,OmniPath
H2BC21 PTPRM 24234451 30021884 physical association cross-linking study IntAct
H2BC5 PTPRM 24234451 30021884 physical association cross-linking study IntAct
PTPRM CTNND1 10753936 15588985 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B2C31 PTPRM 27087310 direct interaction,inhibition N/A NPInter

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