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GENE：SGMS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SGMS2
FullNmae sphingomyelin synthase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28395
EnsembleID ENSG00000164023
Uniprot Q8NHU3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SGMS2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SGMS2 GO:0000139,GO:0002950,GO:0005515,GO:0005654,GO:0005794,GO:0005886,GO:0005886,GO:0006686,GO:0006686,GO:0016301,GO:0016310,GO:0030148,GO:0030500,GO:0033188,GO:0033188,GO:0033188,GO:0046513,GO:0047493,GO:0047493,GO:1905373

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SGMS2 hsa:166929 path:hsa00600 Sphingolipid metabolism - Homo sapiens (human)
SGMS2 hsa:166929 path:hsa01100 Metabolic pathways - Homo sapiens (human)
SGMS2 hsa:166929 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SGMS2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SGMS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 SGMS2 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 SGMS2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 SGMS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000FFE5F SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000759F6E SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001DABC0 SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000246356 SGMS2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LMNA SGMS2 25348397 N/A physical interaction ComPPI
TMPO SGMS2 25348397 N/A physical interaction ComPPI
KIF2C SGMS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LPAR3 SGMS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AKAP5 SGMS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TMPO SGMS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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