GENE：WHRN
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | WHRN |
| FullNmae | whirlin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16361 |
| EnsembleID | ENSG00000095397 |
| Uniprot | Q9P202 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| WHRN | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| WHRN | GO:0001895,GO:0001895,GO:0001917,GO:0001917,GO:0002141,GO:0002142,GO:0002142,GO:0005515,GO:0005737,GO:0005884,GO:0005886,GO:0005929,GO:0007605,GO:0007605,GO:0010628,GO:0021694,GO:0030426,GO:0032391,GO:0032420,GO:0032426,GO:0032426,GO:0036064,GO:0042802,GO:0043025,GO:0045184,GO:0045202,GO:0050910,GO:0050953,GO:0051649,GO:0060088,GO:0060113,GO:0060122,GO:1990075,GO:1990227,GO:1990696 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | WHRN | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | WHRN | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | WHRN | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | WHRN | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | WHRN | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CTCF | WHRN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | WHRN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | WHRN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | WHRN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | WHRN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | WHRN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | WHRN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GOLGA2 | WHRN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VIM | WHRN | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| BMI1 | WHRN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| KEAP1 | WHRN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PXN | WHRN | 24234451 25348397 | physical association | two hybrid,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CASK | WHRN | 22117215 24234451 25348397 | N/A | two hybrid,fluorescence polarization spectroscopy,in vivo | ComPPI,IntAct |
| GPSM2 | WHRN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| COL17A1 | WHRN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| LPXN | WHRN | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| WHRN | TBK1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| WHRN | TBKBP1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| WHRN | MCC | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| WHRN | WDTC1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| WHRN | ANKRD28 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |