Gene Information gene info

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GENE：ITPKC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ITPKC
FullNmae inositol-trisphosphate 3-kinase C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14897
EnsembleID ENSG00000086544
Uniprot Q96DU7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ITPKC immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ITPKC ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ITPKC GO:0005516,GO:0005524,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0008440,GO:0008440,GO:0016310,GO:0016607,GO:0032958,GO:0046854,GO:0051765,GO:0071277

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ITPKC hsa:80271 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
ITPKC hsa:80271 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ITPKC hsa:80271 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
ITPKC hsa:80271 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ITPKC 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ITPKC 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001CC864 ITPKC 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000EF0B ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000009265 ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000058863C ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 ITPKC 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKA ITPKC 25348397 N/A physical interaction ComPPI
PPP3CC ITPKC 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TP53 ITPKC 25348397 N/A physical interaction ComPPI

Visualization










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