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GENE：SS18

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SS18
FullNmae SS18 subunit of BAF chromatin remodeling complex
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11340
EnsembleID ENSG00000141380
Uniprot Q15532

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SS18 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SS18 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SS18 GO:0000226,GO:0000785,GO:0000902,GO:0005515,GO:0005634,GO:0006338,GO:0006357,GO:0008284,GO:0009410,GO:0015630,GO:0016514,GO:0030374,GO:0035556,GO:0045596,GO:0045944,GO:0045944,GO:0048013,GO:0071564,GO:0097150,GO:0140288,GO:1902459

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SS18 hsa:6760 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)
SS18 hsa:6760 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SS18 EGR1 18519690 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SS18 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SS18 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SS18 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SS18 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000821E0 SS18 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000F31F4 SS18 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 SS18 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001597DC SS18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 SS18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C5969 SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA SS18 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 SS18 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF SS18 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SS18 SMARCA4 25361965 interaction type N/A PTMCode2
SMARCA4 SS18 25361965 interaction type N/A PTMCode2
SMARCA2 SS18 25361965 interaction type N/A PTMCode2
SS18 SMARCA2 25361965 interaction type N/A PTMCode2
SMARCB1 SS18 25361965 interaction type N/A PTMCode2
SS18 SMARCB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SMARCE1 SS18 25348397 N/A physical interaction ComPPI
CDKN1A SS18 25348397 N/A physical interaction ComPPI
SMARCC1 SS18 23540691 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTB SS18 23540691 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
YWHAG SS18 25348397 N/A physical interaction ComPPI
TLE1 SS18 25348397 N/A physical interaction ComPPI
EZH2 SS18 25348397 N/A physical interaction ComPPI
GRB2 SS18 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
JUN SS18 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SMARCD1 SS18 25348397 N/A physical interaction ComPPI
EP300 SS18 11030627 25348397 27898060 N/A physical interaction,in vivo ComPPI,OmniPath
CUL3 SS18 25348397 N/A physical interaction ComPPI
RBM14 SS18 16227627 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMARCA4 SS18 23540691 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,physical interaction,in vitro ComPPI,IntAct
NEFM SS18 25348397 N/A physical interaction ComPPI
LRP8 SS18 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ARID1B SS18 25348397 N/A physical interaction ComPPI
SMARCB1 SS18 23540691 24234451 25348397 30108113 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SYNCRIP SS18 25348397 N/A physical interaction ComPPI
HDAC2 SS18 25348397 N/A physical interaction ComPPI
ACTL6A SS18 25348397 N/A physical interaction ComPPI
MDC1 SS18 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
EED SS18 25348397 N/A physical interaction ComPPI
SS18 MLLT10 11423977 25348397 27898060 N/A two hybrid,physical interaction,in vivo ComPPI,OmniPath
SS18 SMARCA2 10072425 11274403 11734557 14603256 22439931 25348397 26186194 26344197 27898060 N/A physical interaction ComPPI,OmniPath
SS18 ELAVL1 25348397 N/A physical interaction ComPPI
SS18 SMARCA5 25348397 N/A physical interaction ComPPI
SS18 HDAC1 25348397 N/A physical interaction ComPPI
SS18 SUZ12 25348397 N/A physical interaction ComPPI
SS18 NFKBID 25348397 N/A physical interaction ComPPI
SS18 DPF3 25348397 N/A physical interaction ComPPI
SS18 DPF2 23540691 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SS18 ARID1A 23540691 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SS18 PHF10 25348397 N/A physical interaction ComPPI
SS18 SMARCC2 25348397 N/A physical interaction ComPPI
SS18 BICRA 25348397 N/A physical interaction ComPPI
SS18 SMARCD3 25348397 N/A physical interaction ComPPI
SS18 SMARCD2 25348397 N/A physical interaction ComPPI
SS18 ARID2 25348397 N/A physical interaction ComPPI
SS18 DPF1 25348397 N/A physical interaction ComPPI
SS18 ACTL6B 25348397 N/A physical interaction ComPPI
SS18 BCL7A 25348397 N/A physical interaction ComPPI
SS18 BCL7C 25348397 N/A physical interaction ComPPI
SS18 BCL7B 25348397 N/A physical interaction ComPPI
SS18 BRD9 25348397 N/A physical interaction ComPPI
SS18 RAB5C 25348397 N/A physical interaction ComPPI
SS18 TTC14 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SS18 EIF3A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SS18 NOP58 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SS18 CNOT2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
H3-3A SS18 25348397 N/A in vivo ComPPI
ATF2 SS18 22439931 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00008BDF29 SS18 27087310 direct interaction,inhibition N/A NPInter

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