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GENE：UHMK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UHMK1
FullNmae U2AF homology motif kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19683
EnsembleID ENSG00000152332
Uniprot Q8TAS1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UHMK1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UHMK1 GO:0003723,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0016607,GO:0016740,GO:0018105,GO:0018105,GO:0018105,GO:0019899,GO:0030424,GO:0031175,GO:0032839,GO:0043021,GO:0043021,GO:0043231,GO:0045948,GO:0045948,GO:0046777,GO:0046825,GO:0046825,GO:0051726,GO:0071598,GO:0071598,GO:0106310,GO:1990935

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UHMK1 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 UHMK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UHMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UHMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UHMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 UHMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 UHMK1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000521626 UHMK1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F6E49 UHMK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA UHMK1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016C318 UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 UHMK1 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000047944F UHMK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE UHMK1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 UHMK1 21572407 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 UHMK1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D50C UHMK1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB UHMK1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 UHMK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 UHMK1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C UHMK1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 UHMK1 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D UHMK1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000157FBE UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000003BF62 UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001799A3 UHMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000204177 UHMK1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED UHMK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 UHMK1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA UHMK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000046CDA6 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000007FBA UHMK1 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000005D4F5 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000007F792 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000E601 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000496C56 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000319E1 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037B2E0 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000118224 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004283FE UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075AEA5 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B13F UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039A25B UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000008AA34 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000038718E UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000260A3A UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000080D0A UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 UHMK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000021D7C8 UHMK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000052EA98 UHMK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 UHMK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005C1F22 UHMK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000D5FFC UHMK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000049FAE8 UHMK1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000036AFF1 UHMK1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
UHMK1 SF1 22135298 phosphorylation N/A PhosphoSite
UHMK1 PIMREG 22135298 phosphorylation N/A PhosphoSite
UHMK1 CDKN1B 22135298 phosphorylation N/A PhosphoSite
UHMK1 STMN1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PAM UHMK1 10574929 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
UHMK1 STMN1 14525934 25348397 7724523 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
UHMK1 ELAVL1 25348397 N/A physical interaction ComPPI
UHMK1 EDEM2 25348397 N/A physical interaction ComPPI
UHMK1 ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
UHMK1 SF1 24234451 25348397 26420826 physical association two hybrid fragment pooling approach ComPPI,IntAct
UHMK1 CDK9 23746844 24234451 association chromatin immunoprecipitation assay IntAct
UHMK1 CDK8 23746844 24234451 association chromatin immunoprecipitation assay IntAct
POLR2A UHMK1 23746844 24234451 association chromatin immunoprecipitation assay IntAct
UHMK1 UHMK1 20876572 30476227 association pull down,x-ray crystallography TheBiogrid
UHMK1 SYN1 10880969 12237306 27898060 N/A N/A OmniPath
UHMK1 STMN1 11135364 19033656 27898060 7724523 inhibition N/A OmniPath
UHMK1 CDKN1B 10831586 12042314 12093740 14504289 15302935 27898060 stimulant N/A OmniPath
UHMK1 CEBPB 1314426 27898060 N/A N/A OmniPath
UHMK1 IQGAP1 15695813 27898060 N/A N/A OmniPath
UHMK1 MBP 10880969 16401070 27898060 inhibition N/A OmniPath
UHMK1 PIMREG 23419774 27898060 stimulant N/A OmniPath
UHMK1 PAM 10574929 19651622 27898060 N/A N/A OmniPath
UHMK1 SF1 16420481 23175611 26420826 27898060 stimulant N/A OmniPath

Visualization










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