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GENE：APCS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol APCS
FullNmae amyloid P component, serum
LocusType gene with protein product
Status Approved
HGNC_id HGNC:584
EnsembleID ENSG00000132703
Uniprot P02743

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
APCS immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
APCS GO:0001849,GO:0001849,GO:0002674,GO:0005509,GO:0005515,GO:0005576,GO:0005576,GO:0005576,GO:0005615,GO:0005615,GO:0005615,GO:0005634,GO:0006457,GO:0006953,GO:0030246,GO:0042802,GO:0044869,GO:0044871,GO:0045087,GO:0045087,GO:0045656,GO:0046597,GO:0046790,GO:0048525,GO:0051082,GO:0051131,GO:0061045,GO:0062023,GO:0070062,GO:0072562,GO:1903016,GO:1903019

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MBL2 APCS 21106539 23180781 physical association enzyme linked immunosorbent assay InnateDB
FCAR APCS 21383176 23180781 physical association surface plasmon resonance InnateDB
PITX3 APCS 22278372 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR APCS 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F1 APCS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 APCS 15378026 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CALU APCS 25361965 interaction type N/A PTMCode2
APCS CALU 25361965 interaction type N/A PTMCode2
APCS FCGR2A 25361965 interaction type N/A PTMCode2
FCGR2A APCS 25361965 interaction type N/A PTMCode2
APCS C4BPA 25361965 interaction type N/A PTMCode2
C4BPA APCS 25361965 interaction type N/A PTMCode2
CRP APCS 25361965 interaction type N/A PTMCode2
APCS CRP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FCGR3A APCS 25348397 N/A physical interaction,in vitro ComPPI
FCGR2B APCS 11359830 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GRB2 APCS 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COPS5 APCS 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
C4BPA APCS 12100475 14525934 25348397 27898060 7592941 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
C1QA APCS 14525934 25348397 27898060 8417122 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
COL4A1 APCS 25348397 27898060 8662978 N/A in vitro ComPPI,OmniPath
TG APCS 14525934 25348397 27898060 3211159 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
LAMA1 APCS 14525934 25348397 27898060 8999915 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
ALX1 APCS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FCGR3B APCS 11359830 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
APCS CRP 14525934 1477104 25348397 27898060 8144569 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
APCS FCGR1A 11359830 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
APCS FN1 12100475 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
APCS HES1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
APCS GOT2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
APCS GK 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CALU APCS 10631319 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
APCS APCS 12126626 14525934 19372378 23850452 24234451 3029048 3172210 8114934 9217261 N/A cross-linking study,experimental interaction detection,mass spectrometry studies of complexes,x-ray crystallography,ion mobility mass spectrometry of complexes HPRD,IntAct

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