Gene Information gene info

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GENE：OXCT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol OXCT1
FullNmae 3-oxoacid CoA-transferase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8527
EnsembleID ENSG00000083720
Uniprot P55809

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
OXCT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
OXCT1 GO:0005739,GO:0005739,GO:0005739,GO:0005759,GO:0008260,GO:0008260,GO:0042182,GO:0046950,GO:0046950,GO:0046952

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
OXCT1 hsa:5019 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
OXCT1 hsa:5019 path:hsa00650 Butanoate metabolism - Homo sapiens (human)
OXCT1 hsa:5019 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
OXCT1 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR OXCT1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 OXCT1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 OXCT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 OXCT1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 OXCT1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 OXCT1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 OXCT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 OXCT1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 OXCT1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001A405B OXCT1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ATP5PO OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
COX5A OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
S100A16 OXCT1 25348397 N/A physical interaction ComPPI
PAK5 OXCT1 25348397 N/A physical interaction ComPPI
PTPN11 OXCT1 25348397 N/A physical interaction ComPPI
MAPK14 OXCT1 25348397 N/A physical interaction ComPPI
NTRK1 OXCT1 25348397 N/A physical interaction ComPPI
NIT1 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PLAUR OXCT1 25348397 N/A physical interaction ComPPI
NME1 OXCT1 25348397 N/A physical interaction ComPPI
C1QBP OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AHNAK OXCT1 25348397 N/A physical interaction ComPPI
CLPB OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
EPS15 OXCT1 25348397 N/A physical interaction ComPPI
TPI1 OXCT1 25348397 N/A physical interaction ComPPI
VAPB OXCT1 25348397 N/A physical interaction ComPPI
CTTN OXCT1 25348397 N/A physical interaction ComPPI
TFCP2 OXCT1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
HSPB1 OXCT1 25348397 N/A physical interaction ComPPI
PRDX6 OXCT1 25348397 N/A physical interaction ComPPI
TIMM23 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SUCLA2 OXCT1 25348397 N/A physical interaction ComPPI
PGK1 OXCT1 25348397 N/A physical interaction ComPPI
PDK1 OXCT1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SVIL OXCT1 25348397 N/A physical interaction ComPPI
WDR1 OXCT1 25348397 N/A physical interaction ComPPI
PSME1 OXCT1 25348397 N/A physical interaction ComPPI
RAE1 OXCT1 25348397 N/A physical interaction ComPPI
THOP1 OXCT1 25348397 N/A physical interaction ComPPI
CLPP OXCT1 24234451 25348397 26058080 association proximity-dependent biotin identification ComPPI,IntAct
TALDO1 OXCT1 25348397 N/A physical interaction ComPPI
SOD1 OXCT1 25348397 N/A physical interaction ComPPI
IQCB1 OXCT1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHMT2 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SUCLG1 OXCT1 25348397 N/A physical interaction ComPPI
HSPD1 OXCT1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TCOF1 OXCT1 25348397 N/A physical interaction ComPPI
PSEN1 OXCT1 21163940 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ADSS2 OXCT1 25348397 N/A physical interaction ComPPI
ATP5F1C OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NRDC OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SDHAF2 OXCT1 25348397 N/A physical interaction ComPPI
NDUFV1 OXCT1 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ECH1 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PHYHIPL OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
HINT1 OXCT1 25348397 N/A physical interaction ComPPI
IDH1 OXCT1 25348397 N/A physical interaction ComPPI
STOML2 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SEPTIN11 OXCT1 25348397 N/A physical interaction ComPPI
SMAP OXCT1 25348397 N/A physical interaction ComPPI
UQCRFS1 OXCT1 25348397 N/A physical interaction ComPPI
LAMC1 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MDH1 OXCT1 25348397 N/A physical interaction ComPPI
PTMS OXCT1 25348397 N/A physical interaction ComPPI
MGST3 OXCT1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TMEM9 OXCT1 25348397 N/A physical interaction ComPPI
MTCH2 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
FH OXCT1 25348397 N/A physical interaction ComPPI
IDE OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
YME1L1 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
TOR1AIP1 OXCT1 25348397 N/A physical interaction ComPPI
LYPLA1 OXCT1 25348397 N/A physical interaction ComPPI
MYG1 OXCT1 25348397 N/A physical interaction ComPPI
CBX3 OXCT1 25348397 N/A physical interaction ComPPI
RBBP7 OXCT1 25348397 N/A physical interaction ComPPI
ATIC OXCT1 25348397 N/A physical interaction ComPPI
MTPN OXCT1 25348397 N/A physical interaction ComPPI
NCL OXCT1 25348397 N/A physical interaction ComPPI
SCAF4 OXCT1 25348397 N/A physical interaction ComPPI
TRMT61B OXCT1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PEDS1 OXCT1 25348397 N/A physical interaction ComPPI
ATP5PF OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFS3 OXCT1 25348397 N/A physical interaction ComPPI
SDHA OXCT1 25348397 N/A physical interaction ComPPI
UBXN7 OXCT1 25348397 N/A physical interaction ComPPI
PTPMT1 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VMA21 OXCT1 25348397 N/A physical interaction ComPPI
MIX23 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SCO2 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SGSH OXCT1 25348397 N/A physical interaction ComPPI
OPA3 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
OXCT1 TIMM9 25348397 N/A physical interaction ComPPI
OXCT1 TMEM177 25348397 N/A physical interaction ComPPI
OXCT1 PRSS35 25348397 N/A physical interaction ComPPI
OXCT1 FMC1 25348397 N/A physical interaction ComPPI
OXCT1 STARD7 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
OXCT1 SCO1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
OXCT1 MICOS13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
OXCT2 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OXCT1 BMP2K 24234451 30021884 physical association cross-linking study IntAct
OXCT1 ADGRB3 24234451 30021884 physical association cross-linking study IntAct

Visualization










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