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GENE：LPAR6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LPAR6
FullNmae lysophosphatidic acid receptor 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15520
EnsembleID ENSG00000139679
Uniprot P43657

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LPAR6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LPAR6 GO:0001835,GO:0005515,GO:0005886,GO:0005886,GO:0007200,GO:0035025,GO:0070915

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LPAR6 hsa:10161 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
LPAR6 hsa:10161 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
LPAR6 hsa:10161 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
LPAR6 hsa:10161 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FOXP3 LPAR6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LPAR6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SMIM3 LPAR6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TYK2 LPAR6 25348397 N/A physical interaction ComPPI
ERBB2 LPAR6 25348397 N/A physical interaction ComPPI
PKP2 LPAR6 25348397 N/A physical interaction ComPPI
JAK1 LPAR6 25348397 N/A physical interaction ComPPI
CAV1 LPAR6 25348397 N/A physical interaction ComPPI
EXOC2 LPAR6 25348397 N/A physical interaction ComPPI
ATM LPAR6 25348397 N/A physical interaction ComPPI
MT-ND1 LPAR6 25348397 N/A physical interaction ComPPI
ZDHHC17 LPAR6 25348397 N/A physical interaction ComPPI
GLMN LPAR6 25348397 N/A physical interaction ComPPI
TUBGCP3 LPAR6 25348397 N/A physical interaction ComPPI
TNPO2 LPAR6 25348397 N/A physical interaction ComPPI
ALG10 LPAR6 25348397 N/A physical interaction ComPPI
STK17B LPAR6 25348397 N/A physical interaction ComPPI
ARL5B LPAR6 25348397 N/A physical interaction ComPPI
SLC38A2 LPAR6 25348397 N/A physical interaction ComPPI
KNTC1 LPAR6 25348397 N/A physical interaction ComPPI
ORAI1 LPAR6 25348397 N/A physical interaction ComPPI
DEGS1 LPAR6 25348397 N/A physical interaction ComPPI
DMD LPAR6 25348397 N/A physical interaction ComPPI
PTPRD LPAR6 25348397 N/A physical interaction ComPPI
VMP1 LPAR6 25348397 N/A physical interaction ComPPI
TTI1 LPAR6 25348397 N/A physical interaction ComPPI
INTS3 LPAR6 25348397 N/A physical interaction ComPPI
NLRX1 LPAR6 25348397 N/A physical interaction ComPPI
NDUFC2 LPAR6 25348397 N/A physical interaction ComPPI
ATL3 LPAR6 25348397 N/A physical interaction ComPPI
LPAR6 GNAQ 15856019 27898060 stimulant N/A OmniPath

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