GENE：GNPAT
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GNPAT |
| FullNmae | glyceronephosphate O-acyltransferase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4416 |
| EnsembleID | ENSG00000116906 |
| Uniprot | O15228 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GNPAT | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GNPAT | GO:0004366,GO:0005777,GO:0005777,GO:0005778,GO:0005778,GO:0005778,GO:0005782,GO:0005829,GO:0006631,GO:0006654,GO:0007416,GO:0007584,GO:0008611,GO:0008611,GO:0008611,GO:0008654,GO:0009410,GO:0016020,GO:0016287,GO:0016287,GO:0016287,GO:0019432,GO:0021587,GO:0030913,GO:0031966,GO:0042594,GO:0061024,GO:0070542 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| GNPAT | hsa:8443 | path:hsa00564 | Glycerophospholipid metabolism - Homo sapiens (human) |
| GNPAT | hsa:8443 | path:hsa04146 | Peroxisome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | GNPAT | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | GNPAT | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | GNPAT | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | GNPAT | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | GNPAT | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | GNPAT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | GNPAT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | GNPAT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| C1QTNF2 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| ZNF544 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| SLC7A1 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| VDR | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| PVR | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| HSPB1 | GNPAT | 24234451 25277244 25348397 | physical association | reverse ras recruitment system,physical interaction | ComPPI,IntAct |
| ATXN3 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| FANCE | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| GRPR | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| BARD1 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| PEX14 | GNPAT | 21525035 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
| PMF1 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| HDAC10 | GNPAT | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | GNPAT | 10215861 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| GNPAT | RAB35 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| GNPAT | PEX5 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | GPR3 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| GNPAT | BSG | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | SLC39A4 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | LYPD3 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | ENPP6 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | MINDY2 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | SCGB2A2 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | ODAD4 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | PACC1 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | DNAAF8 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | FAM131B | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | DCAF11 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | C3AR1 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | IL1R2 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | LYPD4 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | PROSER2 | 25348397 | N/A | physical interaction | ComPPI |
| GNPAT | SLX4 | 19596235 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| GNPAT | CAT | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| HSCB | GNPAT | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |