Gene Information gene info

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GENE：HELZ

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HELZ
FullNmae helicase with zinc finger
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16878
EnsembleID ENSG00000198265
Uniprot P42694

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HELZ pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HELZ immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HELZ GO:0003723,GO:0003723,GO:0004386,GO:0005515,GO:0005524,GO:0005634,GO:0005829,GO:0016020,GO:0016787,GO:0035194,GO:0043186,GO:0046872

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BMI1 HELZ 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR HELZ 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HELZ 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HELZ 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 HELZ 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 HELZ 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 HELZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB HELZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 HELZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004DA9DB HELZ 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 HELZ 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 HELZ 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 HELZ 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 HELZ 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BMI1 HELZ 25348397 N/A physical interaction ComPPI
KEAP1 HELZ 25348397 N/A physical interaction ComPPI
RACK1 HELZ 25348397 N/A physical interaction ComPPI
ARID3A HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GRB2 HELZ 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RB1 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CREBBP HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CELA1 HELZ 25348397 N/A physical interaction ComPPI
CTBP1 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CTBP2 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
BCAT1 HELZ 25348397 N/A physical interaction ComPPI
TUBG1 HELZ 25348397 N/A physical interaction ComPPI
MYC HELZ 25348397 N/A physical interaction ComPPI
STAT5A HELZ 25348397 N/A physical interaction ComPPI
NXF2 HELZ 25348397 N/A physical interaction ComPPI
ERF HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARID3B HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CLTC HELZ 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUMO3 HELZ 17000644 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
RNF2 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NISCH HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NUP50 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ELAVL1 HELZ 25348397 N/A physical interaction ComPPI
ECSIT HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RBFOX2 HELZ 25348397 N/A physical interaction ComPPI
PIGT HELZ 25348397 N/A physical interaction ComPPI
FBXW11 HELZ 25348397 N/A physical interaction ComPPI
RBL1 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CLASRP HELZ 25348397 N/A physical interaction ComPPI
PAN2 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TARDBP HELZ 25348397 N/A physical interaction ComPPI
SMYD3 HELZ 14525934 15235609 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EYA2 HELZ 25348397 N/A physical interaction ComPPI
HELZ SH3YL1 25348397 N/A physical interaction ComPPI
HELZ SIRT7 25348397 N/A physical interaction ComPPI
HELZ SAV1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HELZ NXF1 25348397 N/A physical interaction ComPPI
HELZ KLHL20 25348397 N/A physical interaction ComPPI
HELZ RCBTB1 25348397 N/A physical interaction ComPPI
HELZ CHIA 25348397 N/A physical interaction ComPPI
HELZ CCNJL 25348397 N/A physical interaction ComPPI
HELZ SEC16A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HELZ GAN 25348397 N/A physical interaction ComPPI
HELZ DUSP18 25348397 N/A physical interaction ComPPI
HELZ EYA4 25348397 N/A physical interaction ComPPI
HELZ CELA3A 25348397 N/A physical interaction ComPPI
HELZ ESRP1 25348397 N/A physical interaction ComPPI
HELZ THSD4 25348397 N/A physical interaction ComPPI
HELZ HCFC2 25348397 N/A physical interaction ComPPI
HELZ MARF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ EIF4ENIF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ PCGF5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ PCGF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ KIAA1671 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ POM121B 25348397 N/A physical interaction ComPPI
HELZ POM121C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ C15ORF39 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ FBRS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ POM121 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ PAN3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ EBF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ FBXL19 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HELZ G3BP1 25348397 N/A physical interaction ComPPI
HELZ SOWAHA 24234451 25348397 physical association inference by socio-affinity scoring ComPPI,IntAct
HELZ PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
HELZ NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
HSCB HELZ 24234451 24606901 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct

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