Gene Information gene info

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GENE：HSF4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSF4
FullNmae heat shock transcription factor 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5227
EnsembleID ENSG00000102878
Uniprot Q9ULV5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSF4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSF4 GO:0000122,GO:0000785,GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0003700,GO:0005634,GO:0006357,GO:0016607,GO:0042802,GO:0070306,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAPK3 HSF4 16581800 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,pull down,in-gel kinase assay InnateDB
MAPK1 HSF4 16581800 23180781 physical association anti tag coimmunoprecipitation InnateDB
DUSP26 HSF4 16581800 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
HSF4 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
HIF1A HSF4 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
FOXP3 HSF4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF HSF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HSF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HSF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HSF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 HSF4 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
MAP2K6 HSF4 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
NUDT21 HSF4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DAXX HSF4 25348397 N/A physical interaction ComPPI
CDK2AP2 HSF4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK1 HSF4 14525934 16581800 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MAPK8 HSF4 14525934 16581800 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK3 HSF4 14525934 16581800 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAPK14 HSF4 14525934 16581800 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SMARCA4 HSF4 25348397 N/A physical interaction ComPPI
RABEP1 HSF4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMM13 HSF4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF1 HSF4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 HSF4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF4 SLC27A5 14525934 16552721 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HSF4 DUSP26 14525934 16581800 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HSF4 BCL6 16147992 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF4 FKBP5 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF4 HSF2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF4 TARBP1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF4 MYO15A 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF4 ALKBH4 23145062 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SESTD1 HSF4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBED8 HSF4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSF4 HSF4 10488131 14525934 N/A experimental interaction detection HPRD
MAPK3 HSF4 16581800 27898060 N/A N/A OmniPath
MAP2K6 HSF4 24361130 27898060 N/A N/A OmniPath
MAPK1 HSF4 16581800 27898060 N/A N/A OmniPath
HSF4 MAPK1 16581800 27898060 N/A N/A OmniPath

Visualization










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