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GENE：MYL12A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MYL12A
FullNmae myosin light chain 12A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16701
EnsembleID ENSG00000101608
Uniprot P19105

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MYL12A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MYL12A GO:0001725,GO:0005509,GO:0005515,GO:0005737,GO:0005829,GO:0008360,GO:0016460,GO:0030018,GO:0035254,GO:0070062,GO:0070527,GO:0072659

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MYL12A hsa:10627 path:hsa04360 Axon guidance - Homo sapiens (human)
MYL12A hsa:10627 path:hsa04510 Focal adhesion - Homo sapiens (human)
MYL12A hsa:10627 path:hsa04520 Adherens junction - Homo sapiens (human)
MYL12A hsa:10627 path:hsa04530 Tight junction - Homo sapiens (human)
MYL12A hsa:10627 path:hsa04611 Platelet activation - Homo sapiens (human)
MYL12A hsa:10627 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)
MYL12A hsa:10627 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
MYL12A hsa:10627 path:hsa04814 Motor proteins - Homo sapiens (human)
MYL12A hsa:10627 path:hsa05131 Shigellosis - Homo sapiens (human)
MYL12A hsa:10627 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MYL12A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 MYL12A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MYL12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 MYL12A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BD6DC MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045ED38 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027F5F3 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 MYL12A 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 MYL12A 24297251 direct interaction,mrna cleavage,inhibition experimental interaction detection StarBase

Source Target Pmid Interactiontype Methods Database
GOLGA2 MYL12A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDC73 MYL12A 25348397 N/A physical interaction ComPPI
EIF1B MYL12A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
LIN37 MYL12A 17531812 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TP53BP1 MYL12A 25348397 N/A physical interaction ComPPI
TRAF6 MYL12A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACTB MYL12A 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
KEAP1 MYL12A 25348397 N/A physical interaction ComPPI
MCM2 MYL12A 25348397 N/A physical interaction ComPPI
CD4 MYL12A 25348397 N/A physical interaction ComPPI
SP1 MYL12A 25348397 N/A physical interaction ComPPI
GRB2 MYL12A 12577067 24189400 24234451 25348397 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
JUN MYL12A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
LIG4 MYL12A 25348397 N/A physical interaction ComPPI
CIT MYL12A 21457715 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
PAXIP1 MYL12A 25348397 N/A physical interaction ComPPI
YWHAZ MYL12A 20618440 24234451 25348397 association tandem affinity purification ComPPI,IntAct
CDKN2A MYL12A 17955473 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TNFRSF1A MYL12A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYLK MYL12A 21457715 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
CFTR MYL12A 25348397 N/A physical interaction ComPPI
PDLIM7 MYL12A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VDAC1 MYL12A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ECT2 MYL12A 25348397 N/A physical interaction ComPPI
TNIK MYL12A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LIN9 MYL12A 17531812 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SYNCRIP MYL12A 25348397 N/A physical interaction ComPPI
VHL MYL12A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
OCRL MYL12A 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HSPB1 MYL12A 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
TP63 MYL12A 25348397 N/A anti tag coimmunoprecipitation ComPPI
CHUK MYL12A 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
PTEN MYL12A 25348397 N/A physical interaction ComPPI
MDC1 MYL12A 25348397 N/A physical interaction ComPPI
RIPK3 MYL12A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ITGA4 MYL12A 25348397 N/A physical interaction ComPPI
DNM1L MYL12A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
IGBP1 MYL12A 25348397 N/A physical interaction ComPPI
PRKN MYL12A 25348397 N/A physical interaction ComPPI
SVIL MYL12A 12202484 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CDC42BPA MYL12A 11283256 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
BRCA1 MYL12A 25348397 N/A physical interaction ComPPI
MAP3K3 MYL12A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PARK7 MYL12A 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL13 MYL12A 25348397 N/A physical interaction ComPPI
PRKAB1 MYL12A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKE MYL12A 14743216 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,tandem affinity purification ComPPI,IntAct
RABL6 MYL12A 25348397 N/A physical interaction ComPPI
MYH9 MYL12A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPA1 MYL12A 25348397 N/A physical interaction ComPPI
MCC MYL12A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CYLD MYL12A 25348397 N/A physical interaction ComPPI
SUV39H2 MYL12A 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYL6 MYL12A 25348397 N/A physical interaction ComPPI
UQCRB MYL12A 25348397 N/A physical interaction ComPPI
SLC25A3 MYL12A 25348397 N/A physical interaction ComPPI
MYL9 MYL12A 25348397 N/A physical interaction ComPPI
GLS MYL12A 25348397 N/A physical interaction ComPPI
MYL12A RPL18 25348397 N/A physical interaction ComPPI
MYL12A NDUFB4 25348397 N/A physical interaction ComPPI
MYL12A MRPS21 25348397 N/A physical interaction ComPPI
MYL12A CDKN2A 25348397 N/A physical interaction ComPPI
MYL12A MYH14 25348397 N/A physical interaction ComPPI
MYL12A CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYL12A ZNF746 25348397 N/A physical interaction ComPPI
MYL12A SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MYL12A IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MYL12A PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ESR2 MYL12A 21951318 24234451 association anti tag coimmunoprecipitation IntAct
ROCK1 MYL12A 11283607 12185584 27898060 8702756 stimulant N/A OmniPath
DAPK1 MYL12A 11485996 14600263 15002035 27898060 stimulant N/A OmniPath
DAPK3 MYL12A 10356987 11781833 15096528 27898060 stimulant N/A OmniPath
MYLK MYL12A 17924679 19690332 21457715 27898060 stimulant N/A OmniPath

Visualization










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