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GENE：RAB3A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAB3A
FullNmae RAB3A, member RAS oncogene family
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9777
EnsembleID ENSG00000105649
Uniprot P20336

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAB3A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RAB3A lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
RAB3A lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
RAB3A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAB3A GO:0001669,GO:0001778,GO:0003016,GO:0003924,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005764,GO:0005768,GO:0005829,GO:0005886,GO:0005886,GO:0006887,GO:0006904,GO:0007005,GO:0007274,GO:0007409,GO:0008021,GO:0008021,GO:0009306,GO:0009791,GO:0016079,GO:0016079,GO:0016188,GO:0017156,GO:0017157,GO:0030073,GO:0030324,GO:0030424,GO:0030424,GO:0030667,GO:0030672,GO:0030674,GO:0030742,GO:0031489,GO:0031489,GO:0031630,GO:0031630,GO:0032418,GO:0036465,GO:0043195,GO:0045054,GO:0045055,GO:0045921,GO:0048172,GO:0048471,GO:0048489,GO:0048786,GO:0048790,GO:0050975,GO:0051602,GO:0060201,GO:0060203,GO:0060478,GO:0061202,GO:0061670,GO:0070083,GO:0072659,GO:0097091,GO:0098793,GO:0098794,GO:0099161,GO:1903307,GO:1903561,GO:1905684

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RAB3A hsa:5864 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
RAB3A hsa:5864 path:hsa04911 Insulin secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 RAB3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAB3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RAB3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RAB3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RAB3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NR1I2 RAB3A 21072196 trascriptional regulation,stimulation inferred by curator TFlink
MYC RAB3A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 RAB3A 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000192A75 RAB3A 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KRTAP10-8 RAB3A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAB3A RABGGTB 12535645 14525934 25348397 27898060 7991565 8706741 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
RAB3A CASK 11377421 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
RAB3A CHM 12535645 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAB3A RPH3AL 11134008 12578829 14525934 15159548 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
RAB3A RABAC1 14525934 25348397 9341137 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAB3A SYTL4 11773082 12176990 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RAB3A SYTL5 12051743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RAB3A RAB3IP 14525934 24234451 25348397 25416956 7532276 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
RAB3A RPH3A 10025402 12937130 14525934 24234451 25348397 25416956 physical association experimental interaction detection,physical interaction,mammalian protein protein interaction trap,in vitro,in vivo ComPPI,HPRD,IntAct
RAB3A EGFR 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
RAB3A SNCA 15207266 15854772 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RAB3A PSEN1 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAB3A A2M 25348397 N/A physical interaction ComPPI
RAB3A AP1M2 25348397 N/A physical interaction ComPPI
RAB3A APP 25348397 N/A physical interaction ComPPI
RAB3A ECSIT 25348397 N/A physical interaction ComPPI
RAB3A RNF32 25348397 N/A physical interaction ComPPI
RAB3A ADRB2 25348397 N/A physical interaction ComPPI
RAB3A RAB3B 25348397 N/A physical interaction ComPPI
RAB3A RABGGTA 25348397 N/A physical interaction ComPPI
RAB3A RANGRF 25348397 N/A physical interaction ComPPI
RAB3A WDR45B 25348397 N/A physical interaction ComPPI
RAB3A ARMC1 25348397 N/A physical interaction ComPPI
RAB3A NUFIP1 25348397 N/A physical interaction ComPPI
RAB3A TGOLN2 25348397 N/A physical interaction ComPPI
RAB3A GDI1 25348397 N/A physical interaction ComPPI
RAB3A SLC15A1 25348397 N/A physical interaction ComPPI
RAB3A HAX1 25348397 N/A physical interaction ComPPI
RAB3A GDI2 25348397 N/A physical interaction ComPPI
RAB3A TIMP2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RAB3A OCRL 21378754 24234451 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
CHRM4 RAB3A 24234451 28298427 physical association ubiquitin reconstruction IntAct
GZMB RAB3A 11516400 27898060 stimulant N/A OmniPath
GDI1 RAB3A 27898060 9252412 inhibition N/A OmniPath
RPH3A RAB3A 10025402 12578829 12937130 15099020 25416956 27898060 8262955 8266731 8636125 stimulant N/A OmniPath

Visualization










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