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GENE：SH2D4A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SH2D4A
FullNmae SH2 domain containing 4A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26102
EnsembleID ENSG00000104611
Uniprot Q9H788

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SH2D4A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SH2D4A autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SH2D4A GO:0005515,GO:0005737,GO:0005829,GO:0019902,GO:0019902

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SH2D4A MAGEA11 16189514 23180781 physical association pull down InnateDB
ALAS1 SH2D4A 23180781 25416956 physical association two hybrid InnateDB
TRIM23 SH2D4A 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR SH2D4A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 SH2D4A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SH2D4A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SH2D4A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SH2D4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000044FD7 SH2D4A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 SH2D4A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 SH2D4A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC SH2D4A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 SH2D4A 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKB SH2D4A 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PDE4DIP SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GOLGA2 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF774 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NECAB2 SH2D4A 25348397 N/A physical interaction ComPPI
SORBS3 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STX11 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP1CC SH2D4A 25348397 N/A physical interaction ComPPI
LDOC1 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LZTS2 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCDC172 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAGEA6 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP1CB SH2D4A 17353931 24234451 25348397 25416956 26496610 27107012 27173435 28330616 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach,proximity-dependent biotin identification,validated two hybrid,barcode fusion genetics two hybrid,inference by socio-affinity scoring ComPPI,IntAct
CDR2 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MRFAP1 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CFAP53 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT40 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RINT1 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PNMA1 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DDIT4L SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPRASP2 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPAG5 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PICK1 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LYN SH2D4A 25348397 N/A physical interaction ComPPI
GRAP2 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HCLS1 SH2D4A 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
UBXN11 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SKAP1 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GRB2 SH2D4A 20936779 24234451 25348397 physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach ComPPI,IntAct
PPP1CA SH2D4A 19389623 24234451 25348397 physical association far western blotting,pull down,physical interaction ComPPI,IntAct
PRKAR1B SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STAM2 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DBNL SH2D4A 14525934 16189514 19060904 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
NDRG1 SH2D4A 25348397 N/A physical interaction ComPPI
SORBS2 SH2D4A 25348397 N/A physical interaction ComPPI
CASK SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRAF2 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZBTB16 SH2D4A 25348397 N/A physical interaction ComPPI
TRIM23 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSTPIP1 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TTC19 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IKZF1 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TFIP11 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM27 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BLOC1S2 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GL1 SH2D4A 14525934 16189514 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
TACC1 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MBD3L1 SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC88B SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USHBP1 SH2D4A 25348397 N/A physical interaction ComPPI
EZR SH2D4A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HDGF SH2D4A 25348397 N/A physical interaction ComPPI
MAGEA11 SH2D4A 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
NINL SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CEP76 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ARC SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A ASNS 25348397 N/A physical interaction ComPPI
SH2D4A ALAS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH2D4A VPS52 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH2D4A MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH2D4A HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH2D4A CEP70 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A FSD2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH2D4A NUTM1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH2D4A NXF1 25348397 N/A physical interaction ComPPI
SH2D4A TF 25348397 N/A physical interaction ComPPI
SH2D4A PPP1R7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
SH2D4A TUBA3C 25348397 N/A physical interaction ComPPI
SH2D4A DTD1 25348397 N/A physical interaction ComPPI
SH2D4A OLIG1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SH2D4A MORN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A GRAMD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A PLEKHG4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A TRIML2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A ZMYND12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A CDR2L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A ZNF655 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH2D4A GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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