Gene Information gene info

GENE:XPOT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol XPOT
FullNmae exportin for tRNA
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12826
EnsembleID ENSG00000184575
Uniprot O43592

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
XPOT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
XPOT GO:0000049,GO:0000049,GO:0005515,GO:0005643,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006409,GO:0006886,GO:0016363,GO:0031267,GO:0071528

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
XPOT hsa:11260 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 XPOT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 XPOT 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 XPOT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA XPOT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 XPOT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 XPOT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 XPOT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 XPOT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS XPOT 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000148B91 XPOT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065D58 XPOT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000011A030 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000458AD2 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C85C7 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA XPOT 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 XPOT 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 XPOT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A XPOT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 XPOT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 XPOT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 XPOT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D2F5 XPOT 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 XPOT 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 XPOT 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 XPOT 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 XPOT 25348397 N/A physical interaction ComPPI
RAN XPOT 10944119 11024021 12138183 14525934 24234451 25348397 27898060 9660920 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
KEAP1 XPOT 25348397 N/A physical interaction ComPPI
PSMB2 XPOT 25348397 N/A physical interaction ComPPI
JUN XPOT 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
USP7 XPOT 25348397 N/A physical interaction ComPPI
PSMA3 XPOT 25348397 N/A physical interaction ComPPI
NTRK1 XPOT 25348397 N/A physical interaction ComPPI
XRCC1 XPOT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPRA XPOT 25348397 N/A physical interaction ComPPI
MYC XPOT 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TNFRSF1A XPOT 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HDLBP XPOT 10657246 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
CFTR XPOT 25348397 N/A physical interaction ComPPI
ECT2 XPOT 25348397 N/A physical interaction ComPPI
EPHA1 XPOT 25348397 N/A physical interaction ComPPI
EGFR XPOT 15657067 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TENT5A XPOT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF2 XPOT 25348397 N/A physical interaction ComPPI
HDAC6 XPOT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPRE XPOT 25348397 N/A physical interaction ComPPI
TNFRSF1B XPOT 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CA9 XPOT 25348397 N/A physical interaction ComPPI
RAB9A XPOT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HDAC5 XPOT 25348397 N/A physical interaction ComPPI
NUP153 XPOT 12138183 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RANBP2 XPOT 12138183 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPRN XPOT 25348397 N/A physical interaction ComPPI
AIRE XPOT 25348397 N/A physical interaction ComPPI
TRIM25 XPOT 25348397 N/A physical interaction ComPPI
HTR6 XPOT 25348397 N/A physical interaction ComPPI
XPOT NUP214 12138183 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
XPOT CAMKK2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPOT CLN3 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPOT SIRT7 25348397 N/A physical interaction ComPPI
XPOT FBXO25 25348397 N/A physical interaction ComPPI
XPOT TXNL1 25348397 N/A physical interaction ComPPI
XPOT IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPOT FBXO6 25348397 N/A physical interaction ComPPI
XPOT APEX1 25348397 N/A physical interaction ComPPI
XPOT MCMBP 25348397 N/A physical interaction ComPPI
XPOT PSMA4 25348397 N/A physical interaction ComPPI
XPOT FBXO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPOT MAP3K3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
XPOT RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
XPOT TRA2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XPOT BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
XPOT TGOLN2 24234451 25348397 29568061 association pull down ComPPI,IntAct
XPO7 XPOT 25348397 N/A in vitro ComPPI
ECH1 XPOT 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
CNPY3 XPOT 24234451 30021884 physical association cross-linking study IntAct

Visualization