GENE:XPOT
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | XPOT |
FullNmae | exportin for tRNA |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:12826 |
EnsembleID | ENSG00000184575 |
Uniprot | O43592 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
XPOT | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
XPOT | GO:0000049,GO:0000049,GO:0005515,GO:0005643,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006409,GO:0006886,GO:0016363,GO:0031267,GO:0071528 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
XPOT | hsa:11260 | path:hsa03013 | Nucleocytoplasmic transport - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | XPOT | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | XPOT | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | XPOT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | XPOT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | XPOT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | XPOT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | XPOT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | XPOT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | XPOT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000148B91 | XPOT | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000065D58 | XPOT | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00004719AB | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000260A3A | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000AD02D | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000011A030 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000435A77 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000458AD2 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003CCBB9 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001C85C7 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000007F792 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005E1A16 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000383DF4 | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005606AA | XPOT | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000427B68 | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002233F4 | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003A5E54 | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000008DA94 | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000003E1A9 | XPOT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000451A1 | XPOT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000016FD1A | XPOT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001AFC71 | XPOT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000021D7C8 | XPOT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075C1E1 | XPOT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075D2F5 | XPOT | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000016914 | XPOT | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000821E0 | XPOT | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003758F0 | XPOT | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CUL5 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
RAN | XPOT | 10944119 11024021 12138183 14525934 24234451 25348397 27898060 9660920 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach | ComPPI,HPRD,IntAct,OmniPath |
KEAP1 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
PSMB2 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
JUN | XPOT | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
USP7 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
PSMA3 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
NTRK1 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
XRCC1 | XPOT | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PTPRA | XPOT | 25348397 | N/A | physical interaction | ComPPI |
MYC | XPOT | 17314511 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
TNFRSF1A | XPOT | 14743216 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
HDLBP | XPOT | 10657246 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
CFTR | XPOT | 25348397 | N/A | physical interaction | ComPPI |
ECT2 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
EPHA1 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
EGFR | XPOT | 15657067 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TENT5A | XPOT | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
RNF2 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
HDAC6 | XPOT | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PTPRE | XPOT | 25348397 | N/A | physical interaction | ComPPI |
TNFRSF1B | XPOT | 14743216 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
CA9 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
RAB9A | XPOT | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
HDAC5 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
NUP153 | XPOT | 12138183 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
RANBP2 | XPOT | 12138183 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
PTPRN | XPOT | 25348397 | N/A | physical interaction | ComPPI |
AIRE | XPOT | 25348397 | N/A | physical interaction | ComPPI |
TRIM25 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
HTR6 | XPOT | 25348397 | N/A | physical interaction | ComPPI |
XPOT | NUP214 | 12138183 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
XPOT | CAMKK2 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
XPOT | CLN3 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
XPOT | SIRT7 | 25348397 | N/A | physical interaction | ComPPI |
XPOT | FBXO25 | 25348397 | N/A | physical interaction | ComPPI |
XPOT | TXNL1 | 25348397 | N/A | physical interaction | ComPPI |
XPOT | IQCB1 | 21565611 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
XPOT | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
XPOT | APEX1 | 25348397 | N/A | physical interaction | ComPPI |
XPOT | MCMBP | 25348397 | N/A | physical interaction | ComPPI |
XPOT | PSMA4 | 25348397 | N/A | physical interaction | ComPPI |
XPOT | FBXO7 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
XPOT | MAP3K3 | 14743216 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
XPOT | RIPK4 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
XPOT | TRA2A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
XPOT | BET1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
XPOT | TGOLN2 | 24234451 25348397 29568061 | association | pull down | ComPPI,IntAct |
XPO7 | XPOT | 25348397 | N/A | in vitro | ComPPI |
ECH1 | XPOT | 24234451 25348397 29426014 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
CNPY3 | XPOT | 24234451 30021884 | physical association | cross-linking study | IntAct |