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GENE：BLVRA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BLVRA
FullNmae biliverdin reductase A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1062
EnsembleID ENSG00000106605
Uniprot P53004

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BLVRA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BLVRA GO:0000166,GO:0004074,GO:0004074,GO:0005515,GO:0005829,GO:0005829,GO:0008270,GO:0042167,GO:0070062,GO:0106276,GO:0106277

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BLVRA hsa:644 path:hsa00860 Porphyrin metabolism - Homo sapiens (human)
BLVRA hsa:644 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BLVRA PRKCZ 17639074 23180781 phosphorylation reaction anti tag coimmunoprecipitation,protein kinase assay InnateDB
BLVRA LNX1 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 BLVRA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 BLVRA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 BLVRA 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 BLVRA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 BLVRA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA BLVRA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002C83DA BLVRA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 BLVRA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000032D69B BLVRA 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCD BLVRA 22135298 phosphorylation N/A PhosphoSite
MAPK3 BLVRA 22135298 phosphorylation N/A PhosphoSite
BLVRA BLVRA 22135298 phosphorylation N/A PhosphoSite
BLVRA PRKCB 22135298 phosphorylation N/A PhosphoSite
INSR BLVRA 22135298 phosphorylation N/A PhosphoSite
PRKCA BLVRA 22135298 phosphorylation N/A PhosphoSite
BLVRA MAP2K1 25361965 interaction type N/A PTMCode2
MAP2K1 BLVRA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSCB BLVRA 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
BLVRA LNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BLVRA TLN1 25348397 N/A physical interaction ComPPI
BLVRA TBX20 25348397 N/A physical interaction ComPPI
BLVRA OSBPL6 25348397 N/A physical interaction ComPPI
BLVRA PCYOX1 25348397 N/A physical interaction ComPPI
BLVRA ARF5 25348397 N/A physical interaction ComPPI
BLVRA RTN4IP1 25348397 N/A physical interaction ComPPI
BLVRA OCIAD1 25348397 N/A physical interaction ComPPI
BLVRA RRAGB 25348397 N/A physical interaction ComPPI
BLVRA SNX5 25348397 N/A physical interaction ComPPI
BLVRA DDHD2 25348397 N/A physical interaction ComPPI
BLVRA THBS4 25348397 N/A physical interaction ComPPI
BLVRA THBS3 25348397 N/A physical interaction ComPPI
BLVRA NTRK1 25348397 N/A physical interaction ComPPI
BLVRA DUSP1 25348397 N/A physical interaction ComPPI
BLVRA DUSP19 25348397 N/A physical interaction ComPPI
BLVRA P2RY12 25348397 N/A physical interaction ComPPI
BLVRA DNASE1L2 25348397 N/A physical interaction ComPPI
BLVRA WDR53 25348397 N/A physical interaction ComPPI
BLVRA TRIM25 25348397 N/A physical interaction ComPPI
BLVRA PRKCZ 25348397 N/A physical interaction ComPPI
BLVRA PRKCB 25348397 N/A physical interaction ComPPI
BLVRA MAPK3 18463290 24234451 25348397 N/A physical interaction,protein kinase assay ComPPI,IntAct
BLVRA MAPK1 18463290 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BLVRA MAP2K1 18463290 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BLVRA EZH1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
BLVRA AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BLVRA TUBA1A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BLVRA CERT1 20177069 27898060 N/A N/A OmniPath
PRKCA BLVRA 17639074 22065579 22584576 27898060 N/A N/A OmniPath
BLVRA PRKCB 17227757 27898060 stimulant N/A OmniPath
BLVRA JUND 15870194 27898060 stimulant N/A OmniPath
BLVRA ATF2 15870194 27898060 stimulant N/A OmniPath
PRKCZ BLVRA 17639074 27898060 N/A N/A OmniPath
BLVRA HMOX1 14988408 27898060 stimulant N/A OmniPath
INSR BLVRA 15870194 17639074 27898060 N/A N/A OmniPath
BLVRA JUN 15870194 27898060 stimulant N/A OmniPath

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