GENE：CLIP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CLIP1 |
| FullNmae | CAP-Gly domain containing linker protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10461 |
| EnsembleID | ENSG00000130779 |
| Uniprot | P30622 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CLIP1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CLIP1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CLIP1 | GO:0000278,GO:0000776,GO:0001578,GO:0001726,GO:0005515,GO:0005634,GO:0005813,GO:0005829,GO:0005874,GO:0005874,GO:0005882,GO:0005938,GO:0008017,GO:0008270,GO:0015630,GO:0015631,GO:0030659,GO:0031116,GO:0031116,GO:0031122,GO:0035371,GO:0044354,GO:0051010,GO:0051010 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CLIP1 | hsa:6249 | path:hsa04150 | mTOR signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CLIP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | CLIP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | CLIP1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CLIP1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CLIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CLIP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F2 | CLIP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002C0FCB | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS0000016914 | CLIP1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012A1DD | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008DA94 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FA24D | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000306C70 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000038446A | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A8BB2 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A25B | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B13F | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AEA5 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004283FE | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037B2E0 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000319E1 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000496C56 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD02D | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | CLIP1 | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | CLIP1 | 20371350 21572407 22473208 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000061E50F | CLIP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002394F5 | CLIP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007FBA | CLIP1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E11D | CLIP1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000353492 | CLIP1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | CLIP1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000821E0 | CLIP1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003808EC | CLIP1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | CLIP1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000ECE9C | CLIP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759F6E | CLIP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | CLIP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | CLIP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAPRE1 | CLIP1 | 16455083 24234451 25348397 27173435 | association,physical association | isothermal titration calorimetry,molecular sieving,chromatography technology,pull down,physical interaction,tandem affinity purification,surface plasmon resonance array,inference by socio-affinity scoring | ComPPI,IntAct |
| CDC42 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| NDC80 | CLIP1 | 20664522 24234451 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| TUBB | CLIP1 | 25348397 | N/A | physical interaction,physical interaction,surface plasmon resonance array | ComPPI |
| AMOT | CLIP1 | 24234451 24255178 25348397 | colocalization | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| CALM1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| RAC1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| DPPA4 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| BUB3 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| PLK1 | CLIP1 | 20664522 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| TUBA4A | CLIP1 | 16455083 24234451 25348397 | N/A | affinity chromatography technology,pull down,saturation binding | ComPPI,IntAct |
| DCTN1 | CLIP1 | 12789661 14525934 16362039 24234451 25348397 26638075 | colocalization,association | experimental interaction detection,isothermal titration calorimetry,molecular sieving,static light scattering,x-ray crystallography,physical interaction,imaging technique,surface plasmon resonance array,proximity-dependent biotin identification | ComPPI,HPRD,IntAct |
| IQGAP1 | CLIP1 | 12110184 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| RUNDC3A | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| PAFAH1B1 | CLIP1 | 11940666 14525934 25348397 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| BIN1 | CLIP1 | 19004523 25348397 26506308 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| TUBA1A | CLIP1 | 16954346 17563362 25348397 27898060 | N/A | nuclear magnetic resonance,pull down,physical interaction,surface plasmon resonance array | ComPPI,OmniPath |
| TUBA8 | CLIP1 | 25348397 | N/A | physical interaction,surface plasmon resonance array | ComPPI |
| HDAC6 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| GPS1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| NR3C1 | CLIP1 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| CADPS | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| DYNC1H1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| GORASP1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| BMP1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| MTOR | CLIP1 | 12231510 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| BRCA1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| DAB2IP | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| TUBB1 | CLIP1 | 25348397 | N/A | physical interaction,surface plasmon resonance array | ComPPI |
| CSNK2B | CLIP1 | 20664522 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| MAPRE3 | CLIP1 | 25348397 | N/A | physical interaction,surface plasmon resonance array | ComPPI |
| TUBB3 | CLIP1 | 25348397 | N/A | physical interaction,surface plasmon resonance array | ComPPI |
| PCGF1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| PSMC2 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| POU5F1 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| MAEA | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| CHD4 | CLIP1 | 25348397 | N/A | physical interaction | ComPPI |
| TUBA3C | CLIP1 | 25348397 | N/A | physical interaction,surface plasmon resonance array | ComPPI |
| CLIP1 | NANOGP8 | 25348397 | N/A | physical interaction | ComPPI |
| CLIP1 | NANOG | 25348397 | N/A | physical interaction | ComPPI |
| CLIP1 | TSC22D2 | 25348397 | N/A | physical interaction | ComPPI |
| CLIP1 | CLIP4 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| CLIP1 | MAPRE2 | 14525934 16455083 | N/A | experimental interaction detection | HPRD |
| SERBP1 | CLIP1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| CLIP1 | SLAIN2 | 21646404 27898060 | N/A | N/A | OmniPath |
| PRKCA | CLIP1 | 20519438 27898060 | inhibition | N/A | OmniPath |
| PLK1 | CLIP1 | 20664522 21749319 24451569 27898060 | stimulant | N/A | OmniPath |
| CSNK2A1 | CLIP1 | 20664522 27898060 | stimulant | N/A | OmniPath |
| MTOR | CLIP1 | 12231510 27898060 | stimulant | N/A | OmniPath |
| PAFAH1B1 | CLIP1 | 11940666 12885786 27898060 | stimulant | N/A | OmniPath |
| CLIP1 | DCTN1 | 12789661 15381688 16148041 16362039 17828275 17828277 27898060 | stimulant | N/A | OmniPath |