GENE:DHX33
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DHX33 |
| FullNmae | DEAH-box helicase 33 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16718 |
| EnsembleID | ENSG00000005100 |
| Uniprot | Q9H6R0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DHX33 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DHX33 | GO:0000182,GO:0003723,GO:0003724,GO:0003725,GO:0003725,GO:0003729,GO:0004386,GO:0005515,GO:0005524,GO:0005622,GO:0005634,GO:0005654,GO:0005730,GO:0005730,GO:0005737,GO:0006413,GO:0016887,GO:0032481,GO:0043023,GO:0043410,GO:0045943,GO:0045943,GO:0051092,GO:0072559,GO:0140297,GO:1900227 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| DHX33 | hsa:56919 | path:hsa04621 | NOD-like receptor signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DHX33 | NLRP3 | 23180781 23871209 | physical association | anti tag coimmunoprecipitation | InnateDB |
| DHX33 | PYCARD | 23180781 23871209 | physical association | anti tag coimmunoprecipitation | InnateDB |
| NLRP3 | DHX33 | 23180781 25816776 | physical association | anti tag coimmunoprecipitation | InnateDB |
| DHX33 | ELAVL1 | 19322201 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | DHX33 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | DHX33 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | DHX33 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DHX33 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | DHX33 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000065D58 | DHX33 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS0000324096 | DHX33 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS0000183BED | DHX33 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | DHX33 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000016FD1A | DHX33 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | DHX33 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000003575B | DHX33 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ECFE5 | DHX33 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000184017 | DHX33 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000215483 | DHX33 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | DHX33 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004900F1 | DHX33 | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000FFC8B | DHX33 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002D0FC3 | DHX33 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | DHX33 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | DHX33 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000046CDA6 | DHX33 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076995 | DHX33 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A122A | DHX33 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005D4F5 | DHX33 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | DHX33 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD02D | DHX33 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F0C23 | DHX33 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | DHX33 | 19536157 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000040FA88 | DHX33 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000E601 | DHX33 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | DHX33 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAPK9 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| RPL10 | DHX33 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HNRNPU | DHX33 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RPS6 | DHX33 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| RNF2 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| FOXA1 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| NOP56 | DHX33 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PRPF4 | DHX33 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TERF2 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM33 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| IFI16 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| NLRP3 | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| MPG | DHX33 | 25348397 | N/A | physical interaction | ComPPI |
| MNDA | DHX33 | 24234451 25348397 25665578 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| E2F3 | DHX33 | 22157815 24234451 25348397 | association | pull down | ComPPI,IntAct |
| USP36 | DHX33 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DHX33 | NUDCD1 | 24234451 25036637 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DHX33 | NLRP3 | 23871209 25816776 27898060 | N/A | N/A | OmniPath |
