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GENE：DSN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DSN1
FullNmae DSN1 component of MIS12 kinetochore complex
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16165
EnsembleID ENSG00000149636
Uniprot Q9H410

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DSN1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DSN1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DSN1 GO:0000070,GO:0000444,GO:0000444,GO:0000776,GO:0000776,GO:0000922,GO:0001650,GO:0005515,GO:0005576,GO:0005634,GO:0005654,GO:0005730,GO:0005829,GO:0005829,GO:0008608,GO:0014841,GO:0016604,GO:0035578,GO:0051301

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 DSN1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DSN1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 DSN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DSN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DSN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DSN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DSN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DSN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DSN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DSN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 DSN1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 DSN1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 DSN1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000006FDD4 DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC DSN1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004C5774 DSN1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A DSN1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 DSN1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 DSN1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 DSN1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002A71AD DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000034979B DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 DSN1 21572407 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000004203C DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 DSN1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005CE113 DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DABC0 DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED DSN1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F DSN1 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004818BD DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA DSN1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 DSN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC DSN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 DSN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 DSN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 DSN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000A2C49 DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075ABF4 DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C DSN1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AURKB DSN1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
EXOC5 DSN1 25348397 N/A physical interaction ComPPI
BCAS2 DSN1 25348397 N/A physical interaction ComPPI
RNF40 DSN1 25348397 N/A physical interaction ComPPI
AIMP2 DSN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NDC80 DSN1 21107429 22521787 23589891 23636741 24234451 24402315 25213378 25348397 26157162 26186194 26496610 27705803 27898060 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct,OmniPath
PPP1CC DSN1 25348397 N/A physical interaction ComPPI
PCNA DSN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EGLN3 DSN1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
CBX1 DSN1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
FHL2 DSN1 25348397 N/A physical interaction ComPPI
HGS DSN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIK3R3 DSN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSP90AA1 DSN1 25348397 N/A physical interaction ComPPI
COPA DSN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BUB1 DSN1 20360068 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
UBR5 DSN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP73 DSN1 25348397 N/A physical interaction ComPPI
BRCA2 DSN1 25348397 N/A physical interaction ComPPI
CTDP1 DSN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBX5 DSN1 14525934 15502821 20562864 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
MDC1 DSN1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
BUB1B DSN1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PMF1 DSN1 14525934 15502821 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SALL1 DSN1 25348397 N/A physical interaction ComPPI
PML DSN1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
KIF2B DSN1 25348397 N/A physical interaction ComPPI
ZWINT DSN1 14525934 15502821 15824131 20360068 24234451 25348397 26496610 27705803 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
MIS12 DSN1 14525934 15371340 15502821 20360068 23334297 24234451 25348397 26496610 27705803 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
DSN1 KNL1 23334297 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,molecular sieving,physical interaction,in vivo,tandem affinity purification ComPPI,IntAct
DSN1 NSL1 14525934 14602074 15502821 20231385 20404110 20819936 21075115 22885327 23334297 23589891 24234451 25213378 25348397 26157162 26186194 26496610 27705803 27898060 association anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct,OmniPath
DSN1 CBX3 14525934 15502821 24234451 25348397 27705803 association experimental interaction detection,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
DSN1 SKA2 25348397 N/A physical interaction ComPPI
DSN1 HSP90AA2P 25348397 N/A physical interaction ComPPI
DSN1 SUGT1 25348397 N/A physical interaction ComPPI
DSN1 APP 25348397 N/A physical interaction ComPPI
DSN1 MOV10 25348397 N/A physical interaction ComPPI
DSN1 NXF1 25348397 N/A physical interaction ComPPI
DSN1 MLF1 25348397 N/A physical interaction ComPPI
DSN1 SPC25 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
DSN1 EXOC7 25348397 N/A physical interaction ComPPI
DSN1 SPC24 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
DSN1 EXOC6 25348397 N/A physical interaction ComPPI
DSN1 NUF2 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
DSN1 TTC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSN1 POLR3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSN1 ICE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSN1 MYH9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSN1 CCDC102A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DSN1 CENPC 25348397 N/A physical interaction ComPPI
DSN1 WDFY2 25348397 N/A physical interaction ComPPI
DSN1 ETFB 25348397 N/A physical interaction ComPPI
DSN1 SALL2 25348397 N/A physical interaction ComPPI
RNF20 DSN1 25348397 N/A physical interaction ComPPI
DSN1 DSN1 14525934 15502821 N/A experimental interaction detection HPRD
UBR2 DSN1 23408894 23636741 27898060 N/A N/A OmniPath
AURKB DSN1 18640974 20471944 25601404 25660545 27898060 inhibition N/A OmniPath

Visualization










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