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GENE：FRMD6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FRMD6
FullNmae FERM domain containing 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19839
EnsembleID ENSG00000139926
Uniprot Q96NE9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FRMD6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FRMD6 GO:0003383,GO:0005515,GO:0005737,GO:0005856,GO:0005886,GO:0008104,GO:0032970,GO:0035332,GO:0043296,GO:0098592

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FRMD6 hsa:122786 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
FRMD6 hsa:122786 path:hsa04392 Hippo signaling pathway - multiple species - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR FRMD6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FRMD6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 FRMD6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 FRMD6 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C FRMD6 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 FRMD6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 FRMD6 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FRMD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA FRMD6 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 FRMD6 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F FRMD6 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 FRMD6 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 FRMD6 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 FRMD6 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 FRMD6 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 FRMD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 FRMD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB FRMD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE FRMD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047944F FRMD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF FRMD6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 FRMD6 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GMCL1 FRMD6 25348397 N/A physical interaction ComPPI
EXOC5 FRMD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LZTS2 FRMD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YWHAG FRMD6 15324660 17353931 24234451 24366813 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP2 FRMD6 25348397 N/A physical interaction ComPPI
YWHAB FRMD6 14525934 15324660 17353931 24234451 24366813 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
SNX17 FRMD6 25348397 N/A physical interaction ComPPI
MYC FRMD6 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
DNAJA3 FRMD6 25348397 N/A physical interaction,two hybrid prey pooling approach ComPPI
BLZF1 FRMD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YWHAQ FRMD6 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUV39H1 FRMD6 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
YWHAH FRMD6 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSX2IP FRMD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MID2 FRMD6 25348397 N/A physical interaction ComPPI
IKZF1 FRMD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MLH1 FRMD6 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TSC22D4 FRMD6 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MED4 FRMD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KCTD17 FRMD6 25348397 N/A physical interaction ComPPI
FRMD6 JMJD6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FRMD6 GMCL2 25348397 N/A physical interaction ComPPI
FRMD6 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FRMD6 RASSF7 25348397 N/A physical interaction ComPPI
FRMD6 MAK16 25348397 N/A physical interaction ComPPI
FRMD6 APP 25348397 N/A physical interaction ComPPI
PDIA3 FRMD6 24234451 30021884 physical association cross-linking study IntAct

Visualization










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