Gene Information gene info

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GENE：INTS3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol INTS3
FullNmae integrator complex subunit 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26153
EnsembleID ENSG00000143624
Uniprot Q68E01

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
INTS3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
INTS3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
INTS3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
INTS3 GO:0000724,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0006281,GO:0006974,GO:0010212,GO:0016180,GO:0016180,GO:0032039,GO:0032039,GO:0034243,GO:0035861,GO:0044818,GO:0044818,GO:0070876,GO:0070876

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EED INTS3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 INTS3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 INTS3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 INTS3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 INTS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE INTS3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD INTS3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F INTS3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000321A1A INTS3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A INTS3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1B INTS3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D INTS3 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000221168 INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004D84DB INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003EB4CF INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045ED38 INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027F5F3 INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F373E INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000036AFF1 INTS3 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
INTS3 RPAP2 25361965 interaction type N/A PTMCode2
RPAP2 INTS3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 INTS3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L INTS3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB14 INTS3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP2R1A INTS3 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TP53BP1 INTS3 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
KEAP1 INTS3 25348397 N/A physical interaction ComPPI
ZMYND8 INTS3 25348397 N/A physical interaction ComPPI
CPNE2 INTS3 25348397 N/A physical interaction ComPPI
UBE2N INTS3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
NTRK1 INTS3 25348397 N/A physical interaction ComPPI
SSBP1 INTS3 19759019 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RPA1 INTS3 25348397 N/A physical interaction ComPPI
PPP2CB INTS3 25348397 N/A physical interaction ComPPI
HNRNPL INTS3 25348397 N/A physical interaction ComPPI
PPP2CA INTS3 24234451 25348397 28330616 association pull down ComPPI,IntAct
ZNF592 INTS3 25348397 N/A physical interaction ComPPI
RPA2 INTS3 25348397 N/A physical interaction ComPPI
RPA3 INTS3 25348397 N/A physical interaction ComPPI
CTDP1 INTS3 25348397 N/A physical interaction ComPPI
SOX2 INTS3 25348397 N/A physical interaction ComPPI
CD70 INTS3 25348397 N/A physical interaction ComPPI
POLR2E INTS3 25348397 N/A physical interaction ComPPI
POLR2A INTS3 25348397 N/A physical interaction ComPPI
EED INTS3 25348397 N/A physical interaction ComPPI
RP2 INTS3 25348397 N/A physical interaction ComPPI
UBA1 INTS3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
NFKB1 INTS3 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
TRIM25 INTS3 25348397 N/A physical interaction ComPPI
ELAVL1 INTS3 25348397 N/A physical interaction ComPPI
NBN INTS3 19683501 24234451 25348397 physical association pull down ComPPI,IntAct
PPP2R1B INTS3 25348397 N/A physical interaction ComPPI
TEAD2 INTS3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
POLR2J INTS3 25348397 N/A physical interaction ComPPI
UBE2V1 INTS3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
POLR2C INTS3 25348397 N/A physical interaction ComPPI
POLR2G INTS3 25348397 N/A physical interaction ComPPI
FAF2 INTS3 25348397 N/A physical interaction ComPPI
POLR2D INTS3 25348397 N/A physical interaction ComPPI
POLR2H INTS3 25348397 N/A physical interaction ComPPI
POLR2B INTS3 25348397 N/A physical interaction ComPPI
PNKD INTS3 25348397 N/A physical interaction ComPPI
INTS11 INTS3 24234451 25348397 28396433 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
INTS13 INTS3 25348397 N/A physical interaction ComPPI
INTS1 INTS3 25348397 N/A physical interaction ComPPI
C7ORF26 INTS3 25348397 N/A physical interaction ComPPI
INTS9 INTS3 25348397 N/A physical interaction ComPPI
INTS4 INTS3 25348397 N/A physical interaction ComPPI
ST6GAL1 INTS3 25348397 N/A physical interaction ComPPI
INTS10 INTS3 25348397 N/A physical interaction ComPPI
APP INTS3 25348397 N/A physical interaction ComPPI
CAPZA2 INTS3 25348397 N/A physical interaction ComPPI
E2F3 INTS3 22157815 24234451 25348397 association pull down ComPPI,IntAct
ALDH3A2 INTS3 25348397 N/A physical interaction ComPPI
RPAP2 INTS3 25348397 N/A physical interaction ComPPI
INTS7 INTS3 25348397 N/A physical interaction ComPPI
INTS3 INTS2 25348397 N/A physical interaction ComPPI
INTS3 INTS5 25348397 N/A physical interaction ComPPI
INTS3 INTS6 25348397 N/A physical interaction ComPPI
INTS3 INTS6L 25348397 N/A physical interaction ComPPI
INTS3 INTS8 25348397 N/A physical interaction ComPPI
INTS3 INTS12 25348397 N/A physical interaction ComPPI
INTS3 INTS14 25348397 N/A physical interaction ComPPI
INTS3 NAIF1 25348397 N/A physical interaction ComPPI
INTS3 NABP2 19605351 19683501 20133760 24234451 25348397 26344197 26496610 27898060 28506294 association,physical association anti bait coimmunoprecipitation,molecular sieving,pull down,physical interaction ComPPI,IntAct,OmniPath
INTS3 NABP1 19683501 24234451 25348397 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
INTS3 ZNF687 25348397 N/A physical interaction ComPPI
INTS3 INIP 19683501 24234451 25348397 association,physical association anti bait coimmunoprecipitation,molecular sieving,pull down,physical interaction ComPPI,IntAct
INTS3 ADORA3 25348397 N/A physical interaction ComPPI
INTS3 LPAR6 25348397 N/A physical interaction ComPPI
INTS3 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
INTS3 SIGLECL1 25348397 N/A physical interaction ComPPI
COMTD1 INTS3 25348397 N/A physical interaction ComPPI
BLM INTS3 24234451 28506294 association anti bait coimmunoprecipitation IntAct

Visualization










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