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GENE：LHB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LHB
FullNmae luteinizing hormone subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6584
EnsembleID ENSG00000104826
Uniprot P01229

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LHB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LHB GO:0005102,GO:0005179,GO:0005515,GO:0005576,GO:0005615,GO:0005737,GO:0005796,GO:0006701,GO:0007165,GO:0007186,GO:0007267,GO:0008584,GO:0009755,GO:0061696

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LHB hsa:3972 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
LHB hsa:3972 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
LHB hsa:3972 path:hsa04912 GnRH signaling pathway - Homo sapiens (human)
LHB hsa:3972 path:hsa04913 Ovarian steroidogenesis - Homo sapiens (human)
LHB hsa:3972 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)
LHB hsa:3972 path:hsa04929 GnRH secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LHB 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF LHB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LHB 10319325 18971253 19106114 trascriptional regulation,stimulation inferred by curator TFlink
FOXO1 LHB 22865884 trascriptional regulation,stimulation inferred by curator TFlink
NR5A1 LHB 10319325 19106114 trascriptional regulation,stimulation inferred by curator TFlink
PITX1 LHB 19106114 trascriptional regulation,stimulation inferred by curator TFlink
SF1 LHB 19106114 trascriptional regulation,stimulation inferred by curator TFlink
SP3 LHB N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
LHB LHCGR 25361965 interaction type N/A PTMCode2
LHCGR LHB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FHL3 LHB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGTB LHB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GNAS LHB 14525934 25348397 8663226 N/A experimental interaction detection,in vitro ComPPI,HPRD
GNAI2 LHB 14525934 25348397 8663226 N/A experimental interaction detection,in vitro ComPPI,HPRD
GPHA2 LHB 12045258 24234451 25348397 physical association two hybrid ComPPI,IntAct
LHCGR LHB 14525934 25348397 3470775 N/A experimental interaction detection,in vivo ComPPI,HPRD
CGA LHB 14525934 25348397 27898060 7679977 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
LHB LHCGR 10446903 27898060 3470775 stimulant N/A OmniPath

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