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GENE：MRPS18B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MRPS18B
FullNmae mitochondrial ribosomal protein S18B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14516
EnsembleID ENSG00000204568
Uniprot Q9Y676

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MRPS18B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPS18B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MRPS18B cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
MRPS18B GO:0003735,GO:0003735,GO:0005515,GO:0005654,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0005763,GO:0005763,GO:0005763,GO:0006412,GO:0030054,GO:0032543,GO:0032543

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MRPS18B hsa:28973 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MRPS18B NFKBIL1 17353931 23180781 physical association anti tag coimmunoprecipitation,affinity technology InnateDB
EWSR1 MRPS18B 16189514 23180781 physical association two hybrid,two hybrid pooling approach InnateDB

Source Target Pmid Interactiontype Methods Database
AR MRPS18B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MRPS18B 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A MRPS18B 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 MRPS18B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F1 MRPS18B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 MRPS18B 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 MRPS18B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE MRPS18B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004526F6 MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003CF1AD MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000004CA3 MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037E170 MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE MRPS18B 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 MRPS18B 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
LAT MRPS18B 25348397 N/A two hybrid ComPPI
RBM3 MRPS18B 25348397 N/A physical interaction ComPPI
VCP MRPS18B 25348397 N/A physical interaction ComPPI
MRPS6 MRPS18B 25348397 N/A physical interaction ComPPI
CD81 MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUN MRPS18B 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RB1 MRPS18B 18391203 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
CUL3 MRPS18B 25348397 N/A physical interaction ComPPI
DAP3 MRPS18B 25348397 N/A physical interaction ComPPI
UBC MRPS18B 25348397 N/A physical interaction ComPPI
DLD MRPS18B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBR5 MRPS18B 25348397 N/A physical interaction ComPPI
EWSR1 MRPS18B 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
QARS1 MRPS18B 25348397 N/A physical interaction ComPPI
RPS6 MRPS18B 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
EXOSC6 MRPS18B 25348397 N/A physical interaction ComPPI
TUBGCP3 MRPS18B 25348397 N/A physical interaction ComPPI
PRKN MRPS18B 25348397 N/A physical interaction ComPPI
CAND1 MRPS18B 25348397 N/A physical interaction ComPPI
PDK1 MRPS18B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KARS1 MRPS18B 25348397 N/A physical interaction ComPPI
PARK7 MRPS18B 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
AURKAIP1 MRPS18B 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HNRNPAB MRPS18B 25348397 N/A physical interaction ComPPI
TRA2A MRPS18B 25348397 N/A physical interaction ComPPI
SEC22B MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BET1 MRPS18B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TNFRSF10C MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CEP250 MRPS18B 25348397 N/A physical interaction ComPPI
TUBGCP4 MRPS18B 25348397 N/A physical interaction ComPPI
HSPD1 MRPS18B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MYH9 MRPS18B 25348397 N/A physical interaction ComPPI
MRPS34 MRPS18B 25348397 N/A physical interaction ComPPI
FUS MRPS18B 25348397 N/A physical interaction ComPPI
IGFBP5 MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPA1 MRPS18B 25348397 N/A physical interaction ComPPI
PTCD3 MRPS18B 25348397 N/A physical interaction ComPPI
FBL MRPS18B 24234451 25348397 29568061 association pull down ComPPI,IntAct
MIP MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NEDD1 MRPS18B 25348397 N/A physical interaction ComPPI
MRPS22 MRPS18B 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
MRPS26 MRPS18B 25348397 N/A physical interaction ComPPI
MGST3 MRPS18B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MRPS9 MRPS18B 25348397 N/A physical interaction ComPPI
MRPL12 MRPS18B 22003127 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS31 MRPS18B 25348397 N/A physical interaction ComPPI
ZFPL1 MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LRP10 MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TP53 MRPS18B 25348397 N/A physical interaction ComPPI
MRPS18B NFKBIL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18B MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18B MRPS25 25348397 N/A physical interaction ComPPI
MRPS18B MRPS35 25348397 N/A physical interaction ComPPI
MRPS18B MRPS28 25348397 N/A physical interaction ComPPI
MRPS18B MOV10 25348397 N/A physical interaction ComPPI
MRPS18B TRMT10B 25348397 N/A physical interaction ComPPI
MRPS18B MRPS2 25348397 N/A physical interaction ComPPI
MRPS18B TEPSIN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18B ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPS18B MRPS11 25348397 N/A physical interaction ComPPI
MRPS18B MRPS27 22003127 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18B RNF157 25348397 N/A physical interaction ComPPI
MRPS18B MRPL37 22003127 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18B MRPL45 22003127 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18B MRPS10 22003127 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPS18B SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
MRPS18B BMP10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPS18B TMED8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPS18B SLC35A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPS18B SYS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPS18B CLEC1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MRPL10 MRPS18B 22003127 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRMT61B MRPS18B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TMEM120B MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DHX15 MRPS18B 24234451 29021621 association anti tag coimmunoprecipitation IntAct
H2BC5 MRPS18B 24234451 30021884 physical association cross-linking study IntAct
L1TD1 MRPS18B 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Source Target Pmid Interactiontype Methods Database
URS00009AEF4D MRPS18B 27087310 direct interaction,inhibition N/A NPInter

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