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GENE：NUDT21

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUDT21
FullNmae nudix hydrolase 21
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13870
EnsembleID ENSG00000167005
Uniprot O43809

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUDT21 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NUDT21 GO:0003682,GO:0003723,GO:0003723,GO:0003729,GO:0003729,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005847,GO:0005849,GO:0005849,GO:0005849,GO:0006378,GO:0006397,GO:0006397,GO:0010608,GO:0016604,GO:0030154,GO:0031124,GO:0034451,GO:0035925,GO:0042382,GO:0042802,GO:0042802,GO:0042803,GO:0042826,GO:0051262,GO:0051290,GO:0110104,GO:1990120,GO:2000738,GO:2000975

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NUDT21 hsa:11051 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EZH2 NUDT21 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SRPK1 NUDT21 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 NUDT21 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 NUDT21 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NUDT21 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 NUDT21 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000002103A NUDT21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD NUDT21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F NUDT21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 NUDT21 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003E6EFA NUDT21 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 NUDT21 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002F74F1 NUDT21 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E11D NUDT21 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC NUDT21 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000034B6F5 NUDT21 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 NUDT21 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 NUDT21 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F NUDT21 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 NUDT21 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A NUDT21 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPK NUDT21 22960638 24234451 25348397 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
GOLGA2 NUDT21 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NUDT21 CPSF7 14525934 16189514 24234451 25348397 25416956 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
NUDT21 SNRNP70 14525934 14561889 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
NUDT21 ATXN1 14525934 16713569 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
NUDT21 EXOSC6 14525934 15231747 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NUDT21 RPLP1 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NUDT21 NIF3L1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
NUDT21 RBM48 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NUDT21 CEP126 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
NUDT21 MYL6 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 PSMF1 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NUDT21 CLP1 11060040 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NUDT21 CPSF6 15169763 16189514 21295486 22939629 22960638 24234451 25348397 26344197 26496610 27898060 association,physical association anti bait coimmunoprecipitation,two hybrid,molecular sieving,pull down,x-ray crystallography,physical interaction,ion exchange chromatography,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro ComPPI,IntAct,OmniPath
NUDT21 RNPS1 17353931 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 CD2BP2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 HDAC1 25348397 N/A physical interaction ComPPI
NUDT21 HDAC3 25348397 N/A physical interaction ComPPI
NUDT21 HDAC10 25348397 N/A physical interaction ComPPI
NUDT21 SIRT1 25348397 N/A physical interaction ComPPI
NUDT21 SIRT2 25348397 N/A physical interaction ComPPI
NUDT21 PAPOLA 25348397 N/A physical interaction ComPPI
NUDT21 ITCH 25348397 N/A physical interaction ComPPI
NUDT21 DNMT3L 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 FUNDC2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 SF3B1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 A2M 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 EEF1G 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 DYNC1I1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 EED 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 FBN3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 FLAD1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 SHC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 SLC44A1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 KIFAP3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 SEMA5B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 RNF19A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 DBN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 ZBTB48 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 TRA2A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 JMJD1C 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 F13A1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 PYCR1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 POLR2C 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 HSF4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 RCC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 SEM1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 SEM1 25348397 N/A physical interaction ComPPI
NUDT21 TLE1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 IKZF1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 MASP1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 SNCAIP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 CTNND2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 PTN 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 NGEF 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NUDT21 HNRNPA1 22446626 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
NUDT21 CUL3 25348397 N/A physical interaction ComPPI
NUDT21 CAND1 25348397 N/A physical interaction ComPPI
NUDT21 MTREX 25348397 N/A physical interaction ComPPI
NUDT21 XRCC4 25348397 N/A physical interaction ComPPI
NUDT21 EIF4H 25348397 N/A physical interaction ComPPI
NUDT21 SIPA1L1 25348397 N/A physical interaction ComPPI
NUDT21 FAF1 25348397 N/A physical interaction ComPPI
NUDT21 RPS3 25348397 N/A physical interaction ComPPI
NUDT21 VIM 25348397 N/A physical interaction ComPPI
NUDT21 S100A13 25348397 N/A physical interaction ComPPI
NUDT21 EEFSEC 25348397 N/A physical interaction ComPPI
NUDT21 HDAC2 25348397 N/A physical interaction ComPPI
NUDT21 SMURF1 25348397 N/A physical interaction ComPPI
NUDT21 FN1 25348397 N/A physical interaction ComPPI
NUDT21 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
NUDT21 ITGA4 25348397 N/A physical interaction ComPPI
NUDT21 CD81 25348397 N/A physical interaction ComPPI
NUDT21 NPM1 25348397 N/A physical interaction ComPPI
NUDT21 CARM1 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
NUDT21 SRPK2 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NUDT21 PRPF4B 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NUDT21 SRPK1 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
NUDT21 TCERG1 25348397 N/A physical interaction ComPPI
NUDT21 NEDD4 25348397 N/A physical interaction ComPPI
NUDT21 WWOX 16055720 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
NUDT21 EIF3A 25348397 N/A physical interaction ComPPI
NUDT21 EIF3CL 25348397 N/A physical interaction ComPPI
NUDT21 RPL18 25348397 N/A physical interaction ComPPI
NUDT21 RPA1 25348397 N/A physical interaction ComPPI
NUDT21 RPA2 25348397 N/A physical interaction ComPPI
NUDT21 RPA3 25348397 N/A physical interaction ComPPI
NUDT21 ASB12 25348397 N/A physical interaction ComPPI
NUDT21 MTMR8 25348397 N/A physical interaction ComPPI
NUDT21 FXR2 25348397 N/A physical interaction ComPPI
NUDT21 STAU1 25348397 N/A physical interaction ComPPI
NUDT21 HUWE1 25348397 N/A physical interaction ComPPI
NUDT21 FUS 25348397 N/A physical interaction ComPPI
NUDT21 TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NUDT21 CUL7 25348397 N/A physical interaction ComPPI
NUDT21 OBSL1 25348397 N/A physical interaction ComPPI
NUDT21 EZH2 25348397 N/A physical interaction ComPPI
NUDT21 RNF2 25348397 N/A physical interaction ComPPI
NUDT21 WDR76 25348397 N/A physical interaction ComPPI
NUDT21 ESR1 25348397 N/A physical interaction ComPPI
NUDT21 LMAN1 25348397 N/A physical interaction ComPPI
NUDT21 LRRC47 25348397 N/A physical interaction ComPPI
NUDT21 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NUDT21 RIF1 25348397 N/A physical interaction ComPPI
NUDT21 TXNDC9 25348397 N/A physical interaction ComPPI
NUDT21 PCF11 25348397 N/A physical interaction ComPPI
NUDT21 NTRK1 25348397 N/A physical interaction ComPPI
NUDT21 NUP98 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
NUDT21 TOP3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 CRTAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 MKNK2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 MAPK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 KIF21B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 P3H2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 P3H1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 CDC5L 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NUDT21 WWP2 25348397 N/A physical interaction ComPPI
NUDT21 JMJD6 25348397 N/A physical interaction ComPPI
NUDT21 IKBKE 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NUDT21 RELB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NUDT21 MAP3K7 25348397 N/A tandem affinity purification ComPPI
NUDT21 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 EIF1B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 HLA-C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 TRAF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 MPG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 DEGS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 RXRB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
NUDT21 MAP1LC3B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUDT21 GABARAPL2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUDT21 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUDT21 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUDT21 WWTR1 20972459 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUDT21 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 FAM90A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 S100PBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 TRIM23 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 TEPSIN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 ZRANB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 KRT75 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 ZNF655 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT21 HSCB 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
NUDT21 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NUDT21 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
NUDT21 COQ2 24234451 25348397 29128334 association cross-linking study ComPPI,IntAct
NUDT21 TP53BP1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
NUDT21 MDC1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
NUDT21 NUDT21 14525934 16189514 20479262 24234451 25416956 physical association x-ray crystallography,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach,two hybrid HPRD,IntAct
METTL3 NUDT21 24234451 29507755 association anti tag coimmunoprecipitation IntAct
VIRMA NUDT21 24234451 29507755 association anti tag coimmunoprecipitation IntAct
L1TD1 NUDT21 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B1CFF NUDT21 27087310 direct interaction,inhibition N/A NPInter

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