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GENE：PLOD3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLOD3
FullNmae procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9083
EnsembleID ENSG00000106397
Uniprot O60568

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLOD3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLOD3 GO:0001701,GO:0001886,GO:0005506,GO:0005515,GO:0005615,GO:0005783,GO:0005783,GO:0005783,GO:0005788,GO:0005789,GO:0005791,GO:0005794,GO:0005802,GO:0006493,GO:0008104,GO:0008475,GO:0008475,GO:0008475,GO:0017185,GO:0017185,GO:0017185,GO:0021915,GO:0030199,GO:0031418,GO:0032963,GO:0033823,GO:0033823,GO:0036094,GO:0042311,GO:0046872,GO:0046947,GO:0048730,GO:0050211,GO:0050211,GO:0060425,GO:0062023,GO:0070062,GO:0070831

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLOD3 hsa:8985 path:hsa00310 Lysine degradation - Homo sapiens (human)
PLOD3 hsa:8985 path:hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human)
PLOD3 hsa:8985 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PLOD3 RHOXF2 16189514 23180781 physical association pull down InnateDB
ISG15 PLOD3 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
AR PLOD3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PLOD3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A PLOD3 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF PLOD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PLOD3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D PLOD3 19253296 \N rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS000009262D PLOD3 18927107 19253296 19342589 25416803 mrna cleavage,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS00004929F1 PLOD3 25416803 27233793 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
RHOXF2 PLOD3 14525934 16189514 24234451 25348397 physical association pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
SORBS3 PLOD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KCTD9 PLOD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ISG15 PLOD3 25348397 N/A physical interaction ComPPI
COIL PLOD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GABARAPL2 PLOD3 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CCDC85B PLOD3 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLOD3 EHMT2 14525934 16189514 24234451 25348397 25910212 26028330 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PLOD3 PLOD1 20955792 25348397 27898060 N/A anti tag coimmunoprecipitation ComPPI,OmniPath
PLOD3 FAM153A 14525934 16189514 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
PLOD3 DPPA2 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PLOD3 HNRNPA1 25348397 N/A physical interaction ComPPI
PLOD3 TECPR1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLOD3 MYC 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PLOD3 PPP4C 25348397 N/A physical interaction ComPPI
PLOD3 VHL 25348397 N/A physical interaction ComPPI
PLOD3 CUL3 25348397 N/A physical interaction ComPPI
PLOD3 CAND1 25348397 N/A physical interaction ComPPI
PLOD3 FBXO6 25348397 N/A physical interaction ComPPI
PLOD3 EEF1G 25348397 N/A physical interaction ComPPI
PLOD3 DDX1 25348397 N/A physical interaction ComPPI
PLOD3 DYNLRB1 25348397 N/A physical interaction ComPPI
PLOD3 HADHA 25348397 N/A physical interaction ComPPI
PLOD3 DYNC1H1 25348397 N/A physical interaction ComPPI
PLOD3 HSPD1 25348397 N/A physical interaction ComPPI
PLOD3 EFHC2 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
PLOD3 RAB3IP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PLOD3 COLGALT1 25348397 N/A physical interaction ComPPI
PLOD3 POR 25348397 N/A physical interaction ComPPI
PLOD3 NTRK1 25348397 N/A physical interaction ComPPI
PLOD3 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLOD3 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PLOD3 HNRNPH2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLOD3 PML 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLOD3 TGM2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PLOD3 RHOU 25348397 N/A physical interaction ComPPI
PLOD3 PTPRN 25348397 N/A physical interaction ComPPI
PLOD3 TRIM25 25348397 N/A physical interaction ComPPI
PLOD3 CCND2 25348397 N/A physical interaction ComPPI
PLOD3 CLEC14A 25348397 N/A physical interaction ComPPI
PLOD3 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLOD3 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLOD3 TP53 22653443 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLOD3 ESR1 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
PLOD3 IP6K2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLOD3 NAB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLOD3 KHNYN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLOD3 COL17A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLOD3 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
PLOD3 KSR2 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
EEF1B2 PLOD3 25348397 N/A physical interaction ComPPI
PLOD3 PLOD3 11956192 14525934 N/A experimental interaction detection HPRD
NUDCD1 PLOD3 24234451 29021621 association anti tag coimmunoprecipitation IntAct
PLOD3 TMEM259 24234451 30021884 physical association cross-linking study IntAct
PLOD3 DHX16 24234451 30021884 physical association cross-linking study IntAct
ISG15 PLOD3 16009940 27898060 N/A N/A OmniPath

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