Gene Information gene info

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GENE：SIX3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SIX3
FullNmae SIX homeobox 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10889
EnsembleID ENSG00000138083
Uniprot O95343

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SIX3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SIX3 GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0001222,GO:0001228,GO:0001654,GO:0001654,GO:0002070,GO:0002088,GO:0003404,GO:0005102,GO:0005515,GO:0005634,GO:0005667,GO:0006357,GO:0007420,GO:0007601,GO:0009946,GO:0014016,GO:0021537,GO:0021798,GO:0021846,GO:0021978,GO:0021983,GO:0042127,GO:0045665,GO:0045892,GO:0045944,GO:0061074,GO:0070306,GO:0097402,GO:1901987,GO:1902692,GO:1902742,GO:1990086,GO:1990837,GO:2000177

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SIX3 WNT1 12050133 20710043 20925119 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
PRDM14 SIX3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA SIX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SIX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SIX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SIX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SIX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SIX3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PAX6 SIX3 11554737 trascriptional regulation,stimulation inferred by curator TFlink
PROX1 SIX3 11554737 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BD6DC SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000002103A SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA SIX3 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B SIX3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 SIX3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 SIX3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 SIX3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC SIX3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 SIX3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C SIX3 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000572E11 SIX3 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000028D811 SIX3 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000005A8ED SIX3 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000016D2D4 SIX3 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SIX3 EYA1 25361965 interaction type N/A PTMCode2
EYA1 SIX3 25361965 interaction type N/A PTMCode2
SIX3 PAX6 25361965 interaction type N/A PTMCode2
PAX6 SIX3 25361965 interaction type N/A PTMCode2
GMNN SIX3 25361965 interaction type N/A PTMCode2
SIX3 GMNN 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GMNN SIX3 14525934 14973488 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
TLE1 SIX3 12441302 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TLE3 SIX3 12441302 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
TLE5 SIX3 12050133 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
MTA1 SIX3 25348397 N/A physical interaction ComPPI
PAX6 SIX3 11069920 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SIX3 NR4A3 11173923 12543801 14525934 24234451 25348397 27898060 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo,gal4 vp16 complementation ComPPI,HPRD,IntAct,OmniPath
SIX3 EYA1 10490620 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SIX3 PAX6 11069887 11069920 12072567 27898060 stimulant N/A OmniPath
PAX6 SIX3 11069887 11069920 12072567 27898060 stimulant N/A OmniPath

Visualization










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