Gene Information gene info

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GENE：SLC1A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLC1A1
FullNmae solute carrier family 1 member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10939
EnsembleID ENSG00000106688
Uniprot P43005

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLC1A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLC1A1 GO:0001662,GO:0001932,GO:0001975,GO:0005253,GO:0005313,GO:0005313,GO:0005314,GO:0005314,GO:0005515,GO:0005783,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0006750,GO:0006801,GO:0006811,GO:0006836,GO:0006882,GO:0007212,GO:0007215,GO:0007268,GO:0007420,GO:0007613,GO:0007625,GO:0007626,GO:0009410,GO:0009986,GO:0010460,GO:0010467,GO:0010842,GO:0015108,GO:0015183,GO:0015501,GO:0015501,GO:0015813,GO:0015813,GO:0016020,GO:0016020,GO:0016324,GO:0016595,GO:0019221,GO:0022008,GO:0030424,GO:0030425,GO:0030534,GO:0031901,GO:0031902,GO:0032279,GO:0033229,GO:0033229,GO:0034599,GO:0035633,GO:0036293,GO:0042417,GO:0042802,GO:0042883,GO:0043025,GO:0043083,GO:0043197,GO:0043198,GO:0043204,GO:0043278,GO:0043524,GO:0043679,GO:0045121,GO:0046872,GO:0048514,GO:0048678,GO:0050808,GO:0051938,GO:0055038,GO:0060013,GO:0060047,GO:0060291,GO:0061744,GO:0070062,GO:0070633,GO:0070777,GO:0070778,GO:0070778,GO:0070779,GO:0070779,GO:0071242,GO:0071288,GO:0071314,GO:0071407,GO:0071577,GO:0071944,GO:0072347,GO:0090313,GO:0090461,GO:0097049,GO:0097386,GO:0097440,GO:0098685,GO:0098712,GO:0098712,GO:0098793,GO:0098877,GO:0099170,GO:0099544,GO:0140009,GO:0140009,GO:0140010,GO:0150002,GO:0150104,GO:0150104,GO:1902476,GO:1903712,GO:1903926,GO:1990635,GO:1990708

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SLC1A1 hsa:6505 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
SLC1A1 hsa:6505 path:hsa04724 Glutamatergic synapse - Homo sapiens (human)
SLC1A1 hsa:6505 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 SLC1A1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SLC1A1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 SLC1A1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF SLC1A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SLC1A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SLC1A1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000016FF9C SLC1A1 24304186 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000029D9F1 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003CC709 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 SLC1A1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LMNA SLC1A1 25348397 N/A physical interaction ComPPI
SLC1A1 RNF5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC1A1 EWSR1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SLC1A1 PRKCA 12843260 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SLC1A1 APP 25348397 N/A physical interaction ComPPI
SLC1A1 LDLRAD1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC1A1 LGALS8 25348397 N/A physical interaction ComPPI
SLC1A1 SLAMF1 25348397 N/A physical interaction ComPPI
SLC1A1 NUMBL 25348397 N/A physical interaction ComPPI
SLC1A1 CC2D1A 25348397 N/A physical interaction ComPPI
SLC1A1 INPPL1 25348397 N/A physical interaction ComPPI
SLC1A1 GOLGA7 25348397 N/A physical interaction ComPPI
SLC1A1 ORMDL3 25348397 N/A physical interaction ComPPI
SLC1A1 NDFIP1 25348397 N/A physical interaction ComPPI
SLC1A1 SNX17 25348397 N/A physical interaction ComPPI
SLC1A1 FGFR1 25348397 N/A physical interaction ComPPI
SLC1A1 APOOL 25348397 N/A physical interaction ComPPI
SLC1A1 TNFRSF10B 25348397 N/A physical interaction ComPPI
SLC1A1 EPHA4 25348397 N/A physical interaction ComPPI
SLC1A1 CXCR4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SLC1A1 HNRNPL 25348397 N/A physical interaction ComPPI
SLC1A1 DLG1 24234451 30126976 N/A p8 filamentous phage display IntAct

Visualization










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