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GENE：SPRYD4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPRYD4
FullNmae SPRY domain containing 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:27468
EnsembleID ENSG00000176422
Uniprot Q8WW59

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPRYD4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPRYD4 GO:0003674,GO:0005515,GO:0005634,GO:0008150

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SPRYD4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SPRYD4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SPRYD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPRYD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SPRYD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SPRYD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPRYD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 SPRYD4 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000324096 SPRYD4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00002FC5B0 SPRYD4 20371350 21572407 22473208 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000A07C1 SPRYD4 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00003CF1AD SPRYD4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004ACAAA SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000024DFCE SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 SPRYD4 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F SPRYD4 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS00002D2333 SPRYD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 SPRYD4 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 SPRYD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001CC4BD SPRYD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000031D186 SPRYD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000250A40 SPRYD4 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHCHD2 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CYCS SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GRB2 SPRYD4 16893902 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
CCL5 SPRYD4 25348397 N/A physical interaction ComPPI
POLDIP2 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
C1QBP SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GTF2E2 SPRYD4 25348397 N/A physical interaction ComPPI
PDK1 SPRYD4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SARS2 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GPI SPRYD4 25348397 N/A physical interaction ComPPI
EEF1B2 SPRYD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SHMT2 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPD1 SPRYD4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ARF1 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP5F1C SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A5 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ECH1 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GLS SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
IDE SPRYD4 25348397 N/A physical interaction ComPPI
ATP5MK SPRYD4 25348397 N/A physical interaction ComPPI
MOV10 SPRYD4 25348397 N/A physical interaction ComPPI
NDUFA10 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
CRBN SPRYD4 25348397 N/A physical interaction ComPPI
TRMT61B SPRYD4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ATP5ME SPRYD4 25348397 N/A physical interaction ComPPI
LYRM7 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
GLRX5 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NDUFAB1 SPRYD4 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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