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GENE：STAM2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STAM2
FullNmae signal transducing adaptor molecule 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11358
EnsembleID ENSG00000115145
Uniprot O75886

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STAM2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
STAM2 GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0007165,GO:0016236,GO:0030139,GO:0031901,GO:0033565,GO:0033565,GO:0035091,GO:0036258,GO:0036258,GO:0043130,GO:0043231,GO:0043328,GO:0090148

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STAM2 hsa:10254 path:hsa04144 Endocytosis - Homo sapiens (human)
STAM2 hsa:10254 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR STAM2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 STAM2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 STAM2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 STAM2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR STAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 STAM2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EC1BE STAM2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
FYN STAM2 22135298 phosphorylation N/A PhosphoSite
STAM2 TYK2 25361965 interaction type N/A PTMCode2
TYK2 STAM2 25361965 interaction type N/A PTMCode2
STAM2 EGFR 25361965 interaction type N/A PTMCode2
EGFR STAM2 25361965 interaction type N/A PTMCode2
STAM2 USP8 25361965 interaction type N/A PTMCode2
USP8 STAM2 25361965 interaction type N/A PTMCode2
STAM2 RIN1 25361965 interaction type N/A PTMCode2
RIN1 STAM2 25361965 interaction type N/A PTMCode2
STAM2 HGS 25361965 interaction type N/A PTMCode2
HGS STAM2 25361965 interaction type N/A PTMCode2
STAM2 JAK1 25361965 interaction type N/A PTMCode2
JAK1 STAM2 25361965 interaction type N/A PTMCode2
STAM2 STAMBP 25361965 interaction type N/A PTMCode2
STAMBP STAM2 25361965 interaction type N/A PTMCode2
STAM2 EPS15 25361965 interaction type N/A PTMCode2
EPS15 STAM2 25361965 interaction type N/A PTMCode2
STAM2 JAK2 25361965 interaction type N/A PTMCode2
JAK2 STAM2 25361965 interaction type N/A PTMCode2
STAM2 JAK3 25361965 interaction type N/A PTMCode2
JAK3 STAM2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SF3A3 STAM2 25348397 N/A physical interaction ComPPI
VPS37C STAM2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LCP2 STAM2 17235283 24234451 25348397 25416956 physical association peptide array,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KLHL42 STAM2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP1R13B STAM2 25348397 N/A physical interaction ComPPI
ZFYVE9 STAM2 25348397 N/A physical interaction ComPPI
ARRDC3 STAM2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VCP STAM2 25348397 N/A physical interaction ComPPI
TYK2 STAM2 10899310 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ATXN1 STAM2 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
ZC3H10 STAM2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D1 STAM2 25348397 N/A physical interaction ComPPI
TP53BP2 STAM2 25348397 N/A physical interaction ComPPI
RIN1 STAM2 17403676 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
UBE2D2 STAM2 25348397 N/A physical interaction ComPPI
HGS STAM2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UBC STAM2 12750381 20504764 21121635 22841719 24234451 25348397 26601948 27898060 N/A surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct,OmniPath
ACTN1 STAM2 25348397 N/A physical interaction ComPPI
JAK1 STAM2 10899310 10993906 14525934 24234451 25348397 phosphorylation reaction anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
PTPN1 STAM2 25348397 N/A physical interaction ComPPI
STAM2 JAK3 10899310 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
STAM2 USP8 10982817 13129930 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
STAM2 STAMBP 10899310 14525934 16189514 16730941 19060904 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vivo,two hybrid ComPPI,HPRD,IntAct
STAM2 EPS15 12551915 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
STAM2 XRN1 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
STAM2 DAZAP2 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
STAM2 L3MBTL2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
STAM2 EGFR 10993906 11687594 14525934 17403676 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,confocal microscopy ComPPI,HPRD,IntAct
STAM2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
STAM2 JAK2 10899310 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
STAM2 RNF11 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
STAM2 UBE2D3 25348397 N/A physical interaction ComPPI
STAM2 UBE2H 25348397 N/A physical interaction ComPPI
STAM2 ITCH 25348397 N/A physical interaction ComPPI
STAM2 SEC31A 25348397 N/A physical interaction ComPPI
STAM2 SEC13 25348397 N/A physical interaction ComPPI
STAM2 UBQLN1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STAM2 STAM 25348397 N/A physical interaction ComPPI
STAM2 NAPA 25348397 N/A physical interaction ComPPI
STAM2 KRT8 25348397 N/A physical interaction ComPPI
STAM2 PHF10 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STAM2 KIF15 25348397 N/A physical interaction ComPPI
STAM2 DCAF8 25348397 N/A physical interaction ComPPI
STAM2 SRP19 25348397 N/A physical interaction ComPPI
STAM2 FAM189A2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
STAM2 LITAF 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
STAM2 ABI2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STAM2 PLEKHB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STAM2 SH2D4A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STAM2 MAP3K1 25348397 N/A physical interaction ComPPI
STAM2 TSG101 25348397 N/A physical interaction ComPPI
STAM2 OFD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STAM2 FBF1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STAM2 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STAM2 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
STAM2 XPO1 25348397 N/A physical interaction ComPPI
STAM2 PTPRN2 25348397 N/A physical interaction ComPPI
STAM2 TPTE 25348397 N/A physical interaction ComPPI
STAM2 CDC7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STAM2 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STAM2 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STAM2 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STAM2 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CBX5 STAM2 25348397 N/A physical interaction ComPPI
TIMM8A STAM2 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
COG7 STAM2 25348397 N/A physical interaction ComPPI
PTPN23 STAM2 25348397 N/A physical interaction ComPPI
SRC STAM2 10993906 11687594 27898060 N/A N/A OmniPath
PTPN1 STAM2 20504764 27898060 stimulant N/A OmniPath
FYN STAM2 18626516 27898060 N/A N/A OmniPath
EGFR STAM2 10993906 11687594 15212941 17389395 17403676 19901323 27898060 N/A N/A OmniPath

Visualization










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