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GENE：TIPRL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TIPRL
FullNmae TOR signaling pathway regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30231
EnsembleID ENSG00000143155
Uniprot O75663

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TIPRL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TIPRL GO:0000077,GO:0005515,GO:0005829,GO:0031929,GO:0032515,GO:0043666

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAP3K7 TIPRL 20200282 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TIPRL 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TIPRL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 TIPRL 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TIPRL 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TIPRL 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 TIPRL 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TIPRL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TIPRL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TIPRL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TIPRL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TIPRL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TIPRL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000272A3D TIPRL 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000003ABC4 TIPRL 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000243FF1 TIPRL 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE TIPRL 19536157 22927820 23313552 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000057FDB8 TIPRL 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003BF62 TIPRL 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 TIPRL 19536157 22927820 23313552 23824327 24906430 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00001481F9 TIPRL 19536157 22927820 23313552 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000075BDAA TIPRL 19536157 22927820 23313552 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00001CF056 TIPRL 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00006AA21F TIPRL 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000040FA88 TIPRL 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000040780F TIPRL 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000085F64 TIPRL 22927820 23313552 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00000C48FA TIPRL 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0B46 TIPRL 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC TIPRL 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TIPRL PPP6C 25361965 interaction type N/A PTMCode2
PPP6C TIPRL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UROD TIPRL 25348397 N/A physical interaction ComPPI
TPP2 TIPRL 25348397 N/A physical interaction ComPPI
PPP2R1A TIPRL 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
LMNA TIPRL 25348397 N/A physical interaction ComPPI
PPP4C TIPRL 16085932 17353931 17384681 18614045 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SH3BP1 TIPRL 25348397 N/A physical interaction ComPPI
CUL3 TIPRL 25348397 N/A physical interaction ComPPI
NTRK1 TIPRL 25348397 N/A physical interaction ComPPI
PRDX1 TIPRL 25348397 N/A physical interaction ComPPI
PPP2CB TIPRL 16085932 24234451 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2CA TIPRL 17384681 23892082 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HUWE1 TIPRL 25348397 N/A physical interaction ComPPI
CSE1L TIPRL 25348397 N/A physical interaction ComPPI
IGBP1 TIPRL 23892082 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP6C TIPRL 16085932 17384681 24234451 24255178 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GDA TIPRL 25348397 N/A physical interaction ComPPI
IARS1 TIPRL 25348397 N/A physical interaction ComPPI
DYNLT1 TIPRL 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PPP4R2 TIPRL 16085932 18614045 24234451 25348397 28330616 association anti bait coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
ATP6V1A TIPRL 25348397 N/A physical interaction ComPPI
EIF4A3 TIPRL 25348397 N/A physical interaction ComPPI
UCHL5 TIPRL 25348397 N/A physical interaction ComPPI
SORD TIPRL 25348397 N/A physical interaction ComPPI
MCMBP TIPRL 25348397 N/A physical interaction ComPPI
MSH2 TIPRL 25348397 N/A physical interaction ComPPI
PRDX2 TIPRL 25348397 N/A physical interaction ComPPI
PPP6R3 TIPRL 25348397 N/A physical interaction ComPPI
CORO1B TIPRL 25348397 N/A physical interaction ComPPI
XPNPEP1 TIPRL 25348397 N/A physical interaction ComPPI
ARHGAP44 TIPRL 25348397 N/A physical interaction ComPPI
COMMD2 TIPRL 25348397 N/A physical interaction ComPPI
COMMD4 TIPRL 25348397 N/A physical interaction ComPPI
SLX4 TIPRL 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ITLN1 TIPRL 25348397 N/A physical interaction ComPPI
LARS1 TIPRL 25348397 N/A physical interaction ComPPI
APP TIPRL 25348397 N/A physical interaction ComPPI
PLCG1 TIPRL 25348397 N/A physical interaction ComPPI
TIPRL SSU72 25348397 N/A physical interaction ComPPI
TIPRL EEF1AKMT3 25348397 N/A physical interaction ComPPI
TIPRL NPEPL1 25348397 N/A physical interaction ComPPI
TIPRL ACAD10 25348397 N/A physical interaction ComPPI
TIPRL CORO1C 25348397 N/A physical interaction ComPPI
TIPRL SRM 25348397 N/A physical interaction ComPPI
TIPRL DUSP8 25348397 N/A physical interaction ComPPI
TIPRL FUCA1 25348397 N/A physical interaction ComPPI
TIPRL PTPDC1 25348397 N/A physical interaction ComPPI
TIPRL DYNLT2B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
GOLPH3 TIPRL 25348397 N/A physical interaction ComPPI
MAP3K7 TIPRL 20200282 27898060 N/A N/A OmniPath
TIPRL PPP2CA 17384681 23892082 26344197 27898060 inhibition N/A OmniPath

Visualization










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