Gene Information gene info

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GENE：TJP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TJP2
FullNmae tight junction protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11828
EnsembleID ENSG00000119139
Uniprot Q9UDY2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TJP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TJP2 GO:0004385,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005912,GO:0005923,GO:0005923,GO:0010033,GO:0019904,GO:0030674,GO:0034109,GO:0035633,GO:0044291,GO:0044325,GO:0045216,GO:0045296,GO:0046037,GO:0046710,GO:0050839,GO:0050892,GO:0090557,GO:0090557,GO:0090559,GO:0098609,GO:0150105,GO:1905605,GO:1905605,GO:1990782

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TJP2 hsa:9414 path:hsa04530 Tight junction - Homo sapiens (human)
TJP2 hsa:9414 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TJP2 TJP2 21808241 23829894 26467481 bind,down-regulates N/A Signor

Source Target Pmid Interactiontype Methods Database
AR TJP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 TJP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TJP2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TJP2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TJP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TJP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004DA9DB TJP2 22101077 rna interference,inhibition western blot,quantitative reverse transcription pcr miRSponge
URS00004DA9DB TJP2 22101077 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS00000AA464 TJP2 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 TJP2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 TJP2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000B59A2 TJP2 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
EXOSC5 TJP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF1B TJP2 25348397 N/A physical interaction ComPPI
SH3KBP1 TJP2 12829691 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNAI2 TJP2 25348397 N/A physical interaction ComPPI
CDK6 TJP2 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
TRAF6 TJP2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAG TJP2 14525934 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CLDN2 TJP2 25348397 N/A physical interaction ComPPI
KBTBD7 TJP2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IFI30 TJP2 25348397 N/A physical interaction ComPPI
NUDT12 TJP2 25348397 N/A physical interaction ComPPI
ZYX TJP2 22665060 24234451 25348397 association far western blotting ComPPI,IntAct
OCLN TJP2 10575001 14512431 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK8 TJP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAB TJP2 14525934 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
YWHAZ TJP2 14525934 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
HGS TJP2 25348397 N/A physical interaction ComPPI
CDH1 TJP2 25348397 N/A physical interaction ComPPI
CLK1 TJP2 25348397 N/A physical interaction ComPPI
LASP1 TJP2 22665060 24234451 25348397 association,physical association anti bait coimmunoprecipitation,far western blotting,pull down,proximity ligation assay ComPPI,IntAct
IQGAP1 TJP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CEP135 TJP2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
THOC5 TJP2 25348397 N/A physical interaction ComPPI
MYO18A TJP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHM TJP2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
XPO1 TJP2 25348397 N/A physical interaction ComPPI
YWHAQ TJP2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SRPK1 TJP2 25348397 N/A physical interaction ComPPI
SSTR3 TJP2 19071123 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
ODF2 TJP2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
BCR TJP2 15494376 24234451 25348397 physical association filter binding ComPPI,IntAct
SFN TJP2 15778465 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
YAP1 TJP2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPB1 TJP2 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
UBE2A TJP2 25348397 N/A physical interaction ComPPI
CTNNA1 TJP2 10026224 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NR3C1 TJP2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
LPP TJP2 22665060 24234451 25348397 association far western blotting ComPPI,IntAct
TJP2 SAFB 12403786 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
TJP2 CLDN1 10601346 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TJP2 CGN 10613913 11042084 12023291 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TJP2 SCRIB 15975580 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,two hybrid array,in vitro,in vivo ComPPI,IntAct
TJP2 TJP1 10026224 10966866 14525934 24234451 24255178 25348397 7542259 colocalization experimental interaction detection,physical interaction,proximity-dependent biotin identification ComPPI,HPRD,IntAct
TJP2 EPB41 25348397 N/A physical interaction ComPPI
TJP2 RAE1 25348397 N/A physical interaction ComPPI
TJP2 SRRM2 25348397 N/A physical interaction ComPPI
TJP2 SIRT7 25348397 N/A physical interaction ComPPI
TJP2 UBN1 25348397 N/A physical interaction ComPPI
TJP2 ZMYM3 25348397 N/A physical interaction ComPPI
TJP2 SRPK2 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TJP2 LATS1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 LATS2 25348397 N/A physical interaction ComPPI
TJP2 KIAA1671 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 KIF14 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 PGAM5 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 PLOD1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 KCMF1 25348397 N/A physical interaction ComPPI
TJP2 OBSL1 25348397 N/A physical interaction ComPPI
TJP2 LUZP4 25348397 N/A physical interaction ComPPI
TJP2 SNAI3 25348397 N/A physical interaction ComPPI
TJP2 MAGIX 25348397 N/A physical interaction ComPPI
TJP2 DCAF15 25348397 N/A physical interaction ComPPI
TJP2 LRRC47 25348397 N/A physical interaction ComPPI
TJP2 MCM3 25348397 N/A physical interaction ComPPI
TJP2 PUS7 25348397 N/A physical interaction ComPPI
TJP2 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 CNTRL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 FBF1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TJP2 MYO1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TJP2 MYO19 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TJP2 JPH4 25348397 N/A physical interaction ComPPI
TJP2 CDK15 25348397 N/A physical interaction ComPPI
TJP2 CAPN13 25348397 N/A physical interaction ComPPI
TJP2 ZUP1 25348397 N/A physical interaction ComPPI
TJP2 WWTR1 20850437 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
RPL18 TJP2 24234451 30021884 physical association cross-linking study IntAct
L1TD1 TJP2 24234451 25702638 association anti bait coimmunoprecipitation IntAct
TJP2 WWTR1 20850437 21808241 27898060 inhibition N/A OmniPath
TJP2 YAP1 20868367 23829894 27898060 inhibition N/A OmniPath

Visualization










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