Gene Information gene info

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GENE：VRK3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VRK3
FullNmae VRK serine/threonine kinase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18996
EnsembleID ENSG00000105053
Uniprot Q8IV63

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VRK3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
VRK3 GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0007165,GO:0007519,GO:0018105,GO:0019903,GO:0043231,GO:0070373

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
VRK3 TLR9 17353931 23180781 physical association affinity technology InnateDB

Source Target Pmid Interactiontype Methods Database
AR VRK3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 VRK3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 VRK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
VRK3 BANF1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
RAN VRK3 18617507 24234451 25348397 physical association pull down ComPPI,IntAct
SP4 VRK3 25348397 N/A physical interaction ComPPI
AIM2 VRK3 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
JUN VRK3 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PLK1 VRK3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TSG101 VRK3 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
VRK1 VRK3 18617507 24234451 25348397 association pull down ComPPI,IntAct
FOXP1 VRK3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CSNK2B VRK3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAX VRK3 24234451 25348397 25609649 association,physical association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
DSG1 VRK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TWF2 VRK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FOXD3 VRK3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
VRK3 TXNDC5 25348397 N/A physical interaction ComPPI
VRK3 NR2E1 25348397 N/A physical interaction ComPPI
ZNF524 VRK3 25348397 N/A physical interaction ComPPI
VRK3 TLR9 17353931 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BEEE1 VRK3 27087310 direct interaction,inhibition N/A NPInter

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