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GENE：ATP2B1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP2B1
FullNmae ATPase plasma membrane Ca2+ transporting 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:814
EnsembleID ENSG00000070961
Uniprot P20020

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP2B1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP2B1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATP2B1 GO:0001772,GO:0001818,GO:0003056,GO:0005388,GO:0005388,GO:0005515,GO:0005516,GO:0005524,GO:0005654,GO:0005886,GO:0005886,GO:0008217,GO:0015085,GO:0016020,GO:0016323,GO:0016887,GO:0030165,GO:0030501,GO:0030672,GO:0034220,GO:0042734,GO:0042995,GO:0043231,GO:0046872,GO:0051480,GO:0051480,GO:0051481,GO:0051481,GO:0051928,GO:0070062,GO:0098684,GO:0098978,GO:1900076,GO:1903779,GO:1990034

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP2B1 hsa:490 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04970 Salivary secretion - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
ATP2B1 hsa:490 path:hsa04978 Mineral absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ERBIN ATP2B1 15123239 23180781 physical association peptide array InnateDB
NOS3 ATP2B1 20211863 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 ATP2B1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ATP2B1 19559773 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ATP2B1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ATP2B1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ATP2B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB ATP2B1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029D9F1 ATP2B1 21282569 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 ATP2B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016FD1A ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 ATP2B1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 ATP2B1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 ATP2B1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF ATP2B1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 ATP2B1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000047944F ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B ATP2B1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA ATP2B1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP2B1 YWHAE 25361965 interaction type N/A PTMCode2
YWHAE ATP2B1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAD2L2 ATP2B1 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
CCND1 ATP2B1 25348397 N/A physical interaction ComPPI
CALM1 ATP2B1 25348397 N/A physical interaction ComPPI
SLC38A1 ATP2B1 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
ERBIN ATP2B1 25348397 N/A physical interaction ComPPI
PRKCA ATP2B1 14525934 1827443 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKACA ATP2B1 14525934 25348397 2548572 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAB7A ATP2B1 25348397 N/A physical interaction ComPPI
NTRK1 ATP2B1 25348397 N/A physical interaction ComPPI
CANX ATP2B1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CDH1 ATP2B1 25348397 N/A physical interaction ComPPI
CSNK2A1 ATP2B1 25348397 N/A physical interaction,protein kinase assay ComPPI
HNRNPL ATP2B1 25348397 N/A physical interaction ComPPI
CFTR ATP2B1 25348397 N/A physical interaction ComPPI
NPHP1 ATP2B1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SRPRA ATP2B1 25348397 N/A physical interaction ComPPI
ATP1A1 ATP2B1 25348397 N/A physical interaction ComPPI
EGFR ATP2B1 25348397 N/A physical interaction ComPPI
BCR ATP2B1 15494376 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
YWHAE ATP2B1 18029012 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
RNF2 ATP2B1 25348397 N/A physical interaction ComPPI
ATP2B1 TERF2 25348397 N/A physical interaction ComPPI
ATP2B1 PRKN 25348397 N/A physical interaction ComPPI
ATP2B1 LGR4 25348397 N/A physical interaction ComPPI
ATP2B1 HACD3 25348397 N/A physical interaction ComPPI
ATP2B1 CCDC8 25348397 N/A physical interaction ComPPI
ATP2B1 HSD17B6 25348397 N/A physical interaction ComPPI
ATP2B1 UNK 25348397 N/A physical interaction ComPPI
ATP2B1 GNB2 25348397 N/A physical interaction ComPPI
ATP2B1 HM13 25348397 N/A physical interaction ComPPI
ATP2B1 IDH3A 25348397 N/A physical interaction ComPPI
ATP2B1 CLGN 25348397 N/A physical interaction ComPPI
ATP2B1 RPGRIP1L 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP2B1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP2B1 TOMM40 25348397 N/A physical interaction ComPPI
ATP2B1 ATL3 25348397 N/A physical interaction ComPPI
ATP2B1 TMEM63B 25348397 N/A physical interaction ComPPI
ATP2B1 CENPO 25348397 N/A physical interaction ComPPI
ATP2B1 TUBA1C 25348397 N/A physical interaction ComPPI
ATP2B1 ETS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ATP2B1 CTDSPL 25348397 N/A physical interaction ComPPI
ATP2B1 TRIM25 25348397 N/A physical interaction ComPPI
ATP2B1 HACD1 24234451 25348397 28330616 association pull down ComPPI,IntAct
ATP2B1 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ATP2B1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ATP2B1 TGOLN2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
ATP2B1 CALM2 1332771 14525934 N/A experimental interaction detection HPRD
CCR2 ATP2B1 24234451 28298427 physical association ubiquitin reconstruction IntAct
F2RL1 ATP2B1 24234451 28298427 physical association ubiquitin reconstruction IntAct
ATP2B1 SCRIB 24234451 30126976 N/A p8 filamentous phage display IntAct
H2AC4 ATP2B1 24234451 30021884 physical association cross-linking study IntAct
H1-5 ATP2B1 24234451 30021884 physical association cross-linking study IntAct
H1-2 ATP2B1 24234451 30021884 physical association cross-linking study IntAct
PRKACA ATP2B1 18669648 19651622 20068231 2548572 27898060 9824678 inhibition,stimulant N/A OmniPath
PRKCA ATP2B1 11779484 1827443 27898060 9824678 inhibition N/A OmniPath
CHUK ATP2B1 2548572 27898060 N/A N/A OmniPath
ERBIN ATP2B1 15123239 27898060 N/A N/A OmniPath
CSNK1G1 ATP2B1 12511555 27898060 stimulant N/A OmniPath

Visualization










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