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GENE：LRRFIP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LRRFIP2
FullNmae LRR binding FLII interacting protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6703
EnsembleID ENSG00000093167
Uniprot Q9Y608

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LRRFIP2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LRRFIP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LRRFIP2 GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0016055,GO:0030275

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LRRFIP2 MYD88 21220426 23180781 physical association anti tag coimmunoprecipitation InnateDB
LRRFIP2 DVL3 20006983 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR LRRFIP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LRRFIP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 LRRFIP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 LRRFIP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 LRRFIP2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 LRRFIP2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00004CD810 LRRFIP2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 LRRFIP2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 LRRFIP2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A LRRFIP2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 LRRFIP2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D LRRFIP2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C LRRFIP2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FLII LRRFIP2 25361965 interaction type N/A PTMCode2
LRRFIP2 FLII 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ATPAF2 LRRFIP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KEAP1 LRRFIP2 25348397 N/A physical interaction ComPPI
GRB2 LRRFIP2 12577067 24234451 25348397 association pull down ComPPI,IntAct
CAPZA1 LRRFIP2 25348397 N/A physical interaction ComPPI
CD247 LRRFIP2 24234451 24502978 25348397 association pull down ComPPI,IntAct
IQGAP1 LRRFIP2 25348397 N/A physical interaction ComPPI
CFTR LRRFIP2 17110338 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO18A LRRFIP2 25348397 N/A physical interaction ComPPI
CDK2 LRRFIP2 25348397 N/A physical interaction ComPPI
MYD88 LRRFIP2 25348397 N/A physical interaction ComPPI
FLII LRRFIP2 10366446 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LRRFIP2 ELAVL1 25348397 N/A physical interaction ComPPI
LRRFIP2 UBD 25348397 N/A physical interaction ComPPI
LRRFIP2 PAN2 25348397 N/A physical interaction ComPPI
LRRFIP2 TMOD1 25348397 N/A physical interaction ComPPI
LRRFIP2 IFI16 25348397 N/A physical interaction ComPPI
LRRFIP2 CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LRRFIP2 DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LRRFIP2 MYH9 25348397 N/A physical interaction ComPPI
LRRFIP2 SYNPO 25348397 N/A physical interaction ComPPI
LRRFIP2 MYO5C 25348397 N/A physical interaction ComPPI
LRRFIP2 MYO19 25348397 N/A physical interaction ComPPI
LRRFIP2 STAT3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LRRFIP2 TMOD3 25348397 N/A physical interaction ComPPI
LRRFIP2 TMOD4 25348397 N/A physical interaction ComPPI
LRRFIP2 KARS1 25348397 N/A physical interaction ComPPI
LRRFIP2 RASSF7 25348397 N/A physical interaction ComPPI
LRRFIP2 DVL3 15677333 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
LRRFIP2 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LRRFIP2 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
MYH14 LRRFIP2 24234451 30021884 physical association cross-linking study IntAct
LRRFIP2 PYGL 24234451 30021884 physical association cross-linking study IntAct
MYD88 LRRFIP2 21220426 27898060 N/A N/A OmniPath
LRRFIP2 DVL3 15677333 20006983 27898060 stimulant N/A OmniPath

Visualization










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